Craniopharyngioma: A clinicopathological study of 141 cases |
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Authors: | Dr Seyed Mohammad Tavangar MD Bagher Larijani MD Ali Mahta MD Seyed Mehdi Abdolahzadeh Hosseini MD Masoud Mehrazine MD Fatemeh Bandarian MD |
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Institution: | (1) Department of Pathology, Doctor Shariati Hospital, Tehran University of Medical Sciences, Iran;(2) Endocrinology & Metabolism Research Center, Tehran University of Medical Sciences, Iran;(3) Department of Neurosurgery Doctor Shariati Hospital, Tehran University of Medical Sciences, Iran |
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Abstract: | Craniopharyngioma is a tumor of the suprasellar region that histologically has two distinct variants with some differences
in clinical behavior. The papillary type is almost always seen in adults and has a more indolent course compared with the
adamantinomatous type, which is more common in childhood. In the present study, surgical specimens of craniopharyngiomas from
141 patients were reviewed. Their histomorphologic types were determined and the clinical features and prognosis of each group
were assessed. The sizes of papillary type tumors were smaller and during the follow-up period there was no recurrence in
the squamous papillary group. Aside from surgical resection (total vs subtotal), the recurrence rate for papillary type craniopharyngioma
was lower than for adamantinomatous type. Histologic typing of craniopharyngioma especially in adults is useful for decision
making with regard to treatment and follow-up. |
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Keywords: | Craniopharyngioma adamantinomatous papillary clinicopathologic study |
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