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声门上型喉癌N_0术前放疗的随机对照研究
引用本文:唐平章,张彬,徐国镇,祁永发,李庆宏.声门上型喉癌N_0术前放疗的随机对照研究[J].中华耳鼻咽喉头颈外科杂志,1995(4).
作者姓名:唐平章  张彬  徐国镇  祁永发  李庆宏
作者单位:中国医学科学院肿瘤医院头颈外科,中国医学科学院肿瘤医院放疗科
摘    要:声门上型喉癌临床N_0100例,随机对照研究术前放疗40Gy对控制颈部淋巴结隐匿性转移的作用。放疗加手术(综合治疗组)46例,单纯手术54例,随诊3~12年。综合治疗组颈部复发率为15%(7/46),单纯手术26%(14/54),但无统计学意义,提示40Gy的剂量可能对颈部转移的控制不够。放疗加手术组T_4颈部复发率33%,比T_(1~3)的3.6%明显增高。因此,建议T_4声门上型喉癌应常规做一侧传统的根治性颈清扫术(RND),增加术前或术后放疗剂量到50Gy。

关 键 词:喉肿瘤,癌,鳞状细胞,喉切除术,放射疗法

Pre-operative Radiotherapy for N_0 Supraglottic Carcinoma:a Randomized Study
Tang Pingzhang,Zhang Bin,Xu Guozhen,et al..Pre-operative Radiotherapy for N_0 Supraglottic Carcinoma:a Randomized Study[J].Chinese JOurnal of Otorhinolaryngology Head and Neck Surgery,1995(4).
Authors:Tang Pingzhang  Zhang Bin  Xu Guozhen  
Abstract:A randomized study on 100 patients of No supraglottic squamous cell carcinoma with at least 3 years of follow-up was performed. Surgery alone was used in 56 patients,and combined therapy in 46 patients.The neck failure occurred in 14(26%)patients and 7(15%)patients respectively, there was no statistically difference(P= 0. 287).Neck failure was higher in T_4 stage,therefore, higher dose of radiation and neck dessection should be considered for T_4 supraglottic carcinoma for controlling of regional reeurrence.
Keywords:Laryngeal neoplasms  Carcinoma  squamous cell  Laryngectomy  Radiotherapy
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