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Potassium in hypertension
Authors:Maria Carolina Delgado
Institution:(1) Division of Cardiovascular Medicine, University of Michigan, 3918 Taubman Center, 48109 Ann Arbor, MI, USA
Abstract:Potassium is the most important ion in the living cell, affecting almost every cellular function. Numerous clinical and epidemiologic studies support the knowledge that potassium is a fundamental factor in blood pressure regulation. The role of potassium in blood pressure regulation is reviewed in this article, focusing on its impact on the vascular vessel and the kidney, which are tissues strongly affected by potassium balance. The role of potassium on nitric oxide synthesis and superoxide formation is analyzed. Finally, the study of cell potassium as a marker for hypertension is discussed.
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