联合用药治疗儿童获得性肺炎的临床观察

目的观察β-内酰胺类抗生素联合阿奇霉素治疗儿童获得性肺炎的疗效。方法120例获得性肺炎患儿随机分为对照组60例,观察组60例。对照组60例给予头孢噻肟钠(50～100)mg(/kg·d)静脉滴注治疗,观察组60例在对照组的基础上加阿奇霉素10mg(/kg·d)静脉滴注,观察两组疗效。结果观察组总有效率96.6%高于对照组83.3%(χ2=3.55,P0.05)观察组在发热消退、肺部啰音消失、咳嗽消失、治愈时间均较对照组短(t=3.38、t=4.36、t=5.26、t=6.62、P均0.05)。结论β-内酰胺类抗生素联合阿奇霉素治疗儿童获得性肺炎疗效显著,不良反应少,值得临床推广。

United Remedy for Children Acquired Pneumonia:Clinical Observation

Objective To evaluate the therapeutic efficacy of β-lactam antibiotics combined with azithromycin in the treatrhent of acquired pneumonia in children. Methods Total 120 children with acquired pneumonia were divided randomly into 60 patients in control group and 60 patients in observation group. Both groups received intravenous administration of cefotaxime sodium（50 -100）mg/（kg·d）, and intravenous administration of azithromyein 10mg/ （kg·d）was added to the observation group. The curative effects were observed in the two groups. Results The total effective rate（96.6%） of the observation group was higher than that（83.3%） of the control group（χ^2=3.55, P〈 0.05）. The fever subsiding,pulmonary rales and cough disappearance and healing showed less time in the observation group than those in the control group 0=3.38, t=4.36, t=5.26, t=6.62,P all 〈0.05）. Conclusion β-lactam antibiotics with azithromyc for acquired pneumonia in children can get better a therapeutic effect,with fewer adverse reactions,worthy to be popularized.