| 基因多态性和慢性乙型肝炎干扰素疗效的相关性 |
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| 引用本文： | 张礼周,张振华,李旭. 基因多态性和慢性乙型肝炎干扰素疗效的相关性[J]. 国际流行病学传染病学杂志, 2010, 37(3). DOI: 10.3760/cma.j.issn.1673-4149.2010.03.016 |
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| 作者姓名： | 张礼周 张振华 李旭 |
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| 作者单位： | 安徽医科大学第一附属医院感染科,合肥,230022 |
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| 基金项目： | 973计划前期研究专项课题基金，国家自然科学基金，安徽高校省级自然科学研究项目 |
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| 摘 要： | 影响慢性乙型肝炎(CHB)IFN疗效的因素很多,宿主免疫遗传背景的差异是重要原因之一.最近关于基因多态性和CHB患者IFN疗效的相关性研究越来越多,此文就相关的研究进展进行了简要综述.
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| 关 键 词： | 肝炎,乙型,慢性 干扰素 基因多态性 |
Genetic polymorphism and response to interferon treatment in chronic hepatitis B |
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| ZHANG Li-zhou,ZHANG Zhen-hua,LI Xu. Genetic polymorphism and response to interferon treatment in chronic hepatitis B[J]. International Journal of Epidemiology and Infectious Disease, 2010, 37(3). DOI: 10.3760/cma.j.issn.1673-4149.2010.03.016 |
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| Authors: | ZHANG Li-zhou ZHANG Zhen-hua LI Xu |
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| Abstract: | There are many influence factors of response to interferon treatment in chronic hepatitis B, and the differences of host immunity genetic background is one of the important reasons. Recently, more and more related researches of genetic polymorphisms and response to interferon treatment in chronic hepatitis B are reported, some relative progress are briefly reviewed in the article. |
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| Keywords: | Hepatitis B,chronic Interferons Gene polymorphism |
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