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杜仲水提物对糖尿病大鼠血清和阴茎组织睾酮的影响
引用本文:张万宏,刘子龙,戚玉才,董汉生. 杜仲水提物对糖尿病大鼠血清和阴茎组织睾酮的影响[J]. 中国性科学, 2004, 13(11): 7-8
作者姓名:张万宏  刘子龙  戚玉才  董汉生
作者单位:1. 湖北省武汉市皮肤病防治研究所性学科,武汉,430031
2. 华中科技大学同济医学院计划生育研究所,武汉,430030
3. 湖北省武汉科盾生殖医学门诊,武汉,430010
摘    要:目的:研究杜仲水提物对糖尿病(DM)模型大鼠血清和阴茎组织睾酮(T)水平的影响.方法:采用四氧嘧啶两次给药法建立DM模型;30只DM大鼠随机分为赋形剂组(n=10)、西地那非组(n=10)和杜仲组(n=10).灌胃4周后,用放射免疫法检测血清和阴茎组织匀浆液中的睾酮水平;结果:杜仲组血清和阴茎组织睾酮水平显著高于赋形剂组(P<0.01)和西地那非组(P<0.01).结论:杜仲可提高DM大鼠血清和阴茎组织睾酮水平.

关 键 词:杜仲  糖尿病  睾酮
修稿时间:2004-05-25

Effect of aqueous extract from Eucommia ulmoides on levels of testosterone in serum and penile tissues of diabetic rats
Zhang Wanhong,Liu Zilong,Qiu Yucai,Dong Hansheng. Effect of aqueous extract from Eucommia ulmoides on levels of testosterone in serum and penile tissues of diabetic rats[J]. The Chinese Journal of Human Sexuality, 2004, 13(11): 7-8
Authors:Zhang Wanhong  Liu Zilong  Qiu Yucai  Dong Hansheng
Abstract:Objective:To study the effects of aqueous extract from Eucommia ulmoides Oliv. on the levels of testoster-one(T) in serum and penile tissues of diabetic rats. Methods: Diabetes model was developed by administration of alloxan twice to Sprague Dawley (SD) rats. Thirty diabetic rats were randomly selected and divided into three groups - excipient group (n = 10) , sidenafil group (n = 10) , and Eucommia group (n = 10) . After gavage to the diabetic rats for four weeks, the levels of T in serum and penile tissues were detected by radioimmunoassay. Results: The levels of T in Eucommia group were significantly higher than those in the other two groups (P<0.01).Conclusions:The levels of T in serum and penile tissues of diabetic rats are increased by extract of Eucommia ulmoides .
Keywords:Eucommia ulmoides Oliv  Diabetes mellitus  Testosterone
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