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Intravaginal electrical stimulation as a monotherapy for female stress urinary incontinence: A systematic review and meta-analysis
Affiliation:1. Institute of Sport Sciences, Academy of Physical Education, Mikołowska 72a, 40-065, Katowice, Poland;2. Department of Physiotherapy, Academy of Physical Education, Mikołowska 72a, 40-065, Katowice, Poland;3. Institute of Physiotherapy and Health Sciences, Electromyography and Pelvic Floor Muscles Laboratory, Department of Physical Medicine, Academy of Physical Education, Mikołowska 72a, 40-065, Katowice, Poland;1. South Texas Veteran Health Care System, Audie L. Murphy Veteran Hospital San Antonio, TX, USA;2. National Center for Homelessness Among Veterans, USA;3. Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, USA;4. Durham Veterans Affairs Health Care System, Durham, NC, USA;5. Mid-Atlantic Mental Illness Research, Education, And Clinical Center (MIRECC), Durham, NC, USA;6. Department of Psychology, University of Toledo, Toledo, OH, USA;7. VA Salt Lake City Health Care System and IDEAS Center of Innovation, Salt Lake City UT, USA;8. University of Utah School of Medicine, Department of Medicine, Salt Lake City UT, USA;9. Durham HSRD Center (ADAPT), USA;1. University of Alabama at Birmingham, Division of Hematology/Oncology, 615 18th St S, Suite 2500, Birmingham, AL, 35233, United States;1. The LoveYourBrain Foundation Windsor, Vermont, USA;2. Department of Psychiatry, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA;3. Department of Neurology, Dartmouth-Hitchcock Medical Center, Lebanon, NH, USA;4. Department of Biomedical Data Science, Geisel School of Medicine, Lebanon, NH, USA;1. The Second School of Clinical Medicine, Guangzhou University of Chinese Medicine, Guangzhou, 510405, Guangdong, China;2. Department of Anatomy and Histology & Embryology, Faculty of Basic Medical Science, Kunming Medical University, 1168 West Chunrong Road, Kunming, 650500, Yunnan, China;3. Department of Rehabilitation Medicine, Affiliated Haikou Hospital of Central South University Xiangya School of Medicine, Haikou, 570208, Hainan, China;1. Toros University, Faculty of Health Sciences, Department of Nursing, Mersin, Turkey;2. İnönü University, Faculty of Nursing, Malatya, Turkey;3. Malatya Turgut Özal University Faculty of Health Sciences, Department of Nursing, Malatya, Turkey;4. İnönü University, Medicine School, Nephrology, Malatya, Turkey
Abstract:Background and purposeSince patients, physiotherapists and gynaecologists continue to seek effective conservative treatments for stress urinary incontinence (SUI), the aim of this systematic review and meta-analysis was to determine the therapeutic efficacy of intravaginal electrical stimulation (ES) in women with SUI.MethodsWe searched PubMed, Embase, EBSCOHost and Ovid for randomized controlled trials. For dichotomous data, we calculated the risk ratio (RR) and 95% confidence interval (CI). For continuous data, we calculated the mean difference (MD) and 95% CI. Heterogeneity was assessed with I2 statistics.ResultsOf the 686 records identified, a total of 10 articles met the inclusion criteria. A meta-analysis revealed significant differences between the ES and no active treatment groups in the pooled objective cure rates (RR: 4.20; 95% CI: 1.70 to 10.40; p = 0.001; I2 = 0%) and subjective cure or improvement rates (RR: 4.96; 95%: 1.01 to 24.37; p = 0.04; I2 = 0%). No significant differences were found in the pooled number of incontinence episodes per 24 h (MD: 0.16; 95% CI: 0.68 to 0.37; p = 0.56; I2 = 0%), the pooled Incontinence Quality of Life Questionnaire scores (MD: 1.84; 95% CI: 2.11 to 5.80; p = 0.36; I2 = 0%) or the pooled number of adverse effects (RR: 0.69; 95% CI: 0.38 to 1.27; p = 0.23; I2 = 0%) between the ES and other conservative treatment groups.ConclusionThere was insufficient evidence for or against the use of intravaginal ES therapy for women with SUI, partly due to the variability in the interventions of the included trials and the small number of trials included.
Keywords:Electric stimulation  Female  Therapeutics  Urinary incontinence  SUI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_6rmeE0nSEp"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  stress urinary incontinence  UUI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_7GpooeVvLp"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  urgency urinary incontinence  MUI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_VSPXCCTXJt"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  mixed urinary incontinence  ES"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_qwPFQnq66Z"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  electrical stimulation  PFMs"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_JPCVEdz9DS"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  pelvic floor muscles  RCT"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_bk57z8tgfC"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  randomized controlled trial  PEDro"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_EbaVG1UG5M"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  Physiotherapy Evidence Database  RR"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_WRljwZpkzi"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  risk ratio  D"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_ZyzLFZlWcB"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  mean difference  CI"  },{"  #name"  :"  keyword"  ,"  $"  :{"  id"  :"  pc_2cfXn52W0H"  },"  $$"  :[{"  #name"  :"  text"  ,"  _"  :"  confidence interval
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