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Sudden death due to cirrhotic cardiomyopathy: An autopsy case report
Affiliation:1. Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, 5000, Tunisia;2. Department of Forensic Medicine, Taher Sfar University Hospital, Mahdia, 5100, Tunisia;3. Faculty of Medicine, University of Monastir, Monastir, 5000, Tunisia;1. Department of Pathology, Fattouma Bourguiba University Hospital, Monastir, 5000, Tunisia;2. Department of Forensic Medicine, Taher Sfar University Hospital, Mahdia, 5100, Tunisia;3. Faculty of Medicine, University of Monastir, Monastir, 5000, Tunisia;1. FCFPSL–Professor in Forensic Medicine, Department of Forensic Medicine, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka;2. Consultant Judicial Medical Officer, Teaching Hospital, Kandy, Kandy, Sri Lanka;1. Department of Forensic Medicine, Faculty of Basic Medical Sciences, Chongqing Medical University, Chongqing, 400016, PR China;2. Chongqing Engineering Research Center for Criminal Investigation Technology, Chongqing, 400016, PR China;3. Chongqing Key Laboratory of Forensic Medicine, Chongqing, 400016, PR China;4. Technical Department of Interpol Corps of the Chongqing Public Bureau, Chongqing, China;1. New South Wales Health Education Centre Against Violence, Locked Bag 7118, Parramatta CBD, 2124, Sydney, Australia;2. Sexual Assault Services and Child Protection, Mid North Coast Local Health District, Pacific Highway Coffs Harbour, 2450, Australia;3. Expertise, Evidence and Law Program, School of Law, University of New South Wales, Sydney, 2052, Australia;4. School of Psychology, University of New South Wales, Sydney, 2052, Australia
Abstract:Cirrhosis cardiomyopathy is defined by cardiac dysfunction in cirrhotic patients. It is characterized by the reduced contractile response to stress and/or impaired diastolic relaxation associated with electrophysiological disturbances with unknown cardiac disease.Here we report a case of sudden death in a 44-year-old woman, with no personal and family medical history and in apparently good health before death.The death was occurred when performing agricultural activities. The autopsy revealed an elevated weight of the heart with heterogeneous myocardium. The liver was heavy and had a variegated appearance. The histologic examination showed fibrosis and partially disturbance of the texture of the left ventricular myocardial tissue with storiform patterns and circumscribed hypertrophic cardiomyocytes. The microscopic examination of the liver showed cirrhosis with no specific features of etiology.The death was attributed to arrythmia due to cirrhotic cardiomyopathy.Our case highlighted the importance of pathological examination to con-sider the diagnosis of cirrhotic cardiomyopathy in case of sudden death for patient with known or unknown cirrhosis.
Keywords:Cirrhosis  Cardiomyopathy  Sudden death  Autopsy  Forensic pathology
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