轮状病毒性肠炎68例肠道外临床症状分析

目的：分析轮状病毒性肠炎肠外临床表现的发生状况，了解轮状病毒性肠炎所致多器官损害的特点。方法回顾性分析68例轮状病毒肠炎患儿临床资料，观察出现多脏器损伤的比例，并以发热、酸中毒作为分组标准分析其与肌酸激酶同工酶（ CKMB）异常相关性。结果68例患者中，46例出现CKMB升高，9例心电图出现T波异常，37例出现呼吸道感染症状，10例出现肝功能损伤症状及ALT升高，37例出现酸中毒，6例出现肾脏损伤症状，3例出现皮疹，2例出现无热惊厥；发热、酸中毒与CKMB异常有明显相关性（χ2＝4．390、4．271，均P＜0．05）。结论轮状病毒性肠炎合并肠外多脏器损伤临床较为普遍，预后良好，控制体温及纠正酸中毒可能减少心肌损害。

Parenteral clinical manifestations of 68 cases caused by rotaviral enteritis

Objective To analyze rotaviral enteritis outbreak situation parenteral clinical manifestations and understanding of characteristics of multiple organ damage caused by rotaviral enteritis .Methods The clinical data of 68 cases diagnosed as the infection of rotaviral enteritis were retrospectively analyzed .The proportion of observed ap-pearance of multi-organ damage and fever ,acidosis were used as grouping criteria to analyze the relationship with CK-MB abnormalities.Results In 68 cases,including 46 cases of the elevation of CKMB ,9 cases of ECG T wave abnor-malities,symptoms of respiratory tract infection occurred in 37 patients,10 cases of liver function damage symptoms and increase of ALT,37 cases of acidosis,6 cases with symptoms of kidney damage ,skin rashes in 3 cases,2 cases of non febrile convulsions;fever,acidosis and CKMB anomaly had obvious correlation （χ2 =4.390,4.271,all P 〈0.05 ） .Conclusion Rotaviral enteritis with apparent clinical injury of multiple organ is relatively common .The regu-lar treatments after symptoms are very effective and the prognosis is good .The activity of creatine kinase isoenzyme al-ways is abnormal when the patients have fever ,acidosis ,which suggests that the active control of temperature and cor-rection of acidosis may reduce myocardial injury .