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高压氧在难治性消化性溃疡治疗中的应用
引用本文:李大健,;李英,;刘佳宁.高压氧在难治性消化性溃疡治疗中的应用[J].中国基层医药,2014(10):1466-1467.
作者姓名:李大健  ;李英  ;刘佳宁
作者单位:[1]哈尔滨市第一医院消化内科,黑龙江省哈尔滨150010; [2]哈尔滨市第一医院高压氧科,黑龙江省哈尔滨150010
摘    要:目的:探讨高压氧( HBO)在难治性消化性溃疡治疗中的应用效果。方法回顾性分析259例难治性消化性溃疡患者的临床资料,根据是否行HBO治疗将患者分为高压氧组(127例)和对照组(132例)。比较两组总有效率、幽门螺杆菌( Hp)根除率和复发率。结果高压氧组总有效率、Hp根除率分别为93.7%、92.1%,明显高于对照组的65.2%、56.1%(χ^2=31.97,7.32,均P<0.05);高压氧组复发率为8.4%,明显低于对照组的33.3%(χ^2=12.51,P<0.05)。结论高压氧联合药物治疗难治性消化性溃疡具有更好的疗效。

关 键 词:消化性溃疡  高压氧

Application of hyperbaric oxygen in the treatment of refractory peptic ulcer
Institution:Li Dajian, Li Ying, Liu Jianing (Department of Gasgtroenterology,the First Hospital of Harbin,Harbin,Heilongjiang 150010, China)
Abstract:Objective To explore the application effect of hyperbaric oxygen ( HBO ) in the treatment of refractory peptic ulcer .Methods Clinical data of 259 patients with refractory peptic ulcer were retrospectively ana-lyzed.According to whether received HBO therapy , these patients were divided into the HBO group ( n=127 ) and control group(n=132).The total effective rate,Helicobacter pylori(Hp) eradication rate and relapse rate of the two groups were compared .Results The total effective rate ,Hp eradication rate of the HBO group were 93.7%,92.1%, respectively,which were significantly higher than 65.2%,56.1% of the control group (χ2 =31.97,7.32,all P〈0.05).The relapse rate of the HBO group was 8.4%,which was significantly lower than 33.3%of the control group (χ^2 =12.51,P〈0.05).Conclusion HBO combined with conventional drug in the treatment of refractory peptic ulcer has significant effect .
Keywords:Peptic ulcer  Hyperbaric oxygenation
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