酪酸梭菌二联活菌散治疗小儿肺炎继发性腹泻疗效观察

目的：观察酪酸梭菌二联活菌散在小儿肺炎继发性腹泻治疗中的疗效。方法选取肺炎继发性腹泻患儿82例，按入院顺序分成两组，对照组42例给予蒙脱石散（思密达）对症治疗继发性腹泻，观察组40例在其基础上口服酪酸梭菌二联活菌散。统计两组患儿腹泻治疗时间及住院时间，并对两组患儿的临床疗效进行评价。结果观察组总有效率为95．0％，明显高于对照组的71．4％，组间差异有统计学意义（χ2＝8.05，P＜0．05）；观察组腹泻持续时间[（2．3＆#177;1．1） d]、肺炎治疗疗程[（4．4＆#177;1．9） d]、住院时间[（4．5＆#177;2．1）d]均明显短于对照组的[（4．4＆#177;1．6）d]、[（6．8＆#177;2．3）d]、[（7．1＆#177;2．4）d]（t＝7．39、7．35、7．39，均P＜0.05）。结论采用酪酸梭菌二联活菌散治疗小儿肺炎继发性腹的疗效显著，值得临床推广应用。

The efficacy of the bivalent of clostridium butyricum powder in the treatment of childhood diarrhea after pneumonia

Objective To observe the efficacy of the bivalent of clostridium butyricum powder in the treat-ment of childhood diarrhea after pneumonia .Methods 82 cases of patients with childhood diarrhea after pneumonia in our hospital were divided into two groups according to hospital sequence .42 cases of the control group were given symptomatic treatment with smecta and the 40 cases of the study group used bivalent of clostridium butyricum powder in basis of the control group .The diarrhea treatment time and length of stay ,the efficacy of the treatment were com-pared between the two groups .Results The total effective rate of the study group was 95.0% significantly higher than 71.4%of the control group,the difference was statistically significant （χ2 =8.05,P＆lt;0.05）.The study group′s duration of diarrhea were （2.3 ＆#177;1.1）d,pneumonia duration of treatment were （4.4 ＆#177;1.9）d,length of hospital stay were（4.5 ＆#177;2.1）d significantly lower than those of the control group ,the differences were statistically significant （t=7.39,7.35,7.39,all P＆lt;0.05）.Conclusion The bivalent of clostridium butyricum powder has a significant effect in the treatment of childhood diarrhea after pneumonia , which is worth to be applied in clinical application .