江苏省南通地区0~7岁儿童急性下呼吸道感染常见病毒病原学分析 |
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引用本文: | 盛凯华,;徐美玉,;孙宝兰,;黄祖辉. 江苏省南通地区0~7岁儿童急性下呼吸道感染常见病毒病原学分析[J]. 中国基层医药, 2014, 0(11): 1607-1609 |
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作者姓名: | 盛凯华, 徐美玉, 孙宝兰, 黄祖辉 |
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作者单位: | [1]启东市人民医院儿科,江苏省启东226200; [2]南通大学附属医院儿科;,江苏省启东226200; [3]不详,江苏省启东226200; |
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基金项目: | 江苏省南通市科技计划项目(HS12972) |
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摘 要: | 目的 了解江苏省南通地区0~7岁急性下呼吸道感染(ALRI)住院患儿常见病毒感染情况及其临床特征.方法 收集2012年1月至2013年3月因ALRI住院的0~7岁患儿鼻咽部拭子标本1 376份,采用直接免疫荧光法对呼吸道合胞病毒(RSV)、腺病毒(ADV)、流感病毒A、B(IVA、IVB)、副流感病毒Ⅰ~Ⅲ(PIV Ⅰ~Ⅲ)进行检测,并结合临床资料分析检测结果.结果 1 376份呼吸道标本中,577例(41.93%)病毒阳性,其中RSV阳性376例(65.16%),ADV阳性42例(7.28%),IVA阳性63例(10.92%),IVB阳性24例(4.16%),PIV Ⅰ阳性20例(3.47%),PIVⅡ阳性19例(3.29%),PIVⅢ阳性108例(18.72%).混合感染68例(11.79%)[2种病毒阳性59例(86.76%),3种病毒阳性9例(13.24%)].各年龄组中,0~6个月组病毒检出率最高(53.32%),5~7岁最低(6.90%).2012年3月份(58.67%)、12月份(53.33%)和2013年1月(53.63%)病毒检出率高于其他月份,其中2012年6月份病毒检出率最低(33.33%).ALRI中毛细支气管炎病毒检出率最高(69.23%).结论 江苏省南通地区0~7岁儿童ALRI的主要病原是病毒感染,不同年龄、季节、病种,病毒的感染率存在差异.婴幼儿为呼吸道常见病毒感染的主要人群.
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关 键 词: | 呼吸道感染 腺病毒,人 呼吸道合胞病毒 流感病毒 儿童 |
The aetiological analysis of common viruses of acute lower respiratory infection among the hospitalized children 0 to 7 years old in Nantong of Jiangsu |
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Affiliation: | Sheng Kaihua,Xu Meiyu, Sun Baolan, Huang Zuhui.( Department of Pediatrics ,the People's Hospital of Qidong, Qidong ,Jiangsu 226200, China) |
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Abstract: | Objective To investigate the infection status and clinical features of common viruses in acute lower respiratory infection (ALRI) among the hospitalized children 0 to 7 years old in Nantong of Jiangsu.Methods 1 376 swab samples from pharynx nasalis in the ALRI inpatients 0 to 7 years old were collected.The human respiratory syncytial virus (RSV),adenovirus (ADV),influenza virusA,B (IVA,B),parainfluenza virus Ⅰ ~ Ⅲ (PIV Ⅰ ~ Ⅲ)were detected by direct immunofluorescence assay,and the results were analyzed.Results In 1 376 respiratory tract samples,there were 577 cases(41.93%) of positive samples.In all positive samples,there were 376 cases of RSVpositive (65.16%),42 ADV-positive (7.28%),63 IVA-positive (10.92%),24 IVB-positive (4.16%),20 PIV Ⅰ-positive(3.47%),19 PIV Ⅱ-positive (3.29%),108 PIV Ⅲ-positive (18.72%),68 cases with mixed infection (11.79%) [two virus-positive ones in 59 cases (86.76%),three virus-positive ones in 9 cases (13.24%)].In different age group,the highest positive rate was in 0 ~ 6-month-old group(53.32%),with the lowest in 5-7 years old group(6.90%).Virus detection rate was higher in March 2012 (58.67%),December 2012 (53.33%),and January 2013(53.63%)than the rest months,including the lowest June 2012(33.33%).Bronchiolitis virus detection rate was the highest(69.23%)among ALRI.Conclusion The virus is major pathogen of children 0 to 7 years old with ALRI in Nantong of Jiangsu,and with difference among different ages,seasons and diseases.Infants and young children are the main affected population. |
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Keywords: | Respiratory tract infections Adenoviruses, human Respiratory syncytial viruses Influenza viruses Child |
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