丙泊酚、芬太尼复合小剂量咪达唑仑静脉麻醉在妇产科治疗中的应用

目的：分析丙泊酚、芬太尼复合小剂量咪达唑仑在妇产科临床应用中的麻醉效果。方法120例妇产科门诊手术患者，按照就诊顺序随机分为对照组和观察组，对照组使用丙泊酚复合芬太尼进行麻醉，观察组使用丙泊酚、芬太尼复合小剂量咪达唑仑进行麻醉。比较两组患者手术中R、HR、SaO2和平均动脉压（ MAR），记录麻醉起效时间、恢复时间、丙泊酚用量及不良反应等情况。结果对照组麻醉后的R、HR、SaO2、MAR最低值与麻醉前相比，差异具有统计学意义（t＝6．328、9．917、9．476、4．458，均P＜0．01）；观察组麻醉后的R、HR、SaO2、MAR最低值与麻醉前相比，差异亦具有统计学意义（ t＝4．467、9．351、2．999、3.979，均P＜0.01）；观察组药物起效时间及丙泊酚用量均显著低于对照组（ t＝4．435、6．017，均P＜0.01）；两组手术后不良反应发生率差异无统计学意义（P＞0．05）。结论在妇产科门诊手术的麻醉中，丙泊酚、芬太尼复合小剂量咪达唑仑具有麻醉效果较好，镇痛镇静效果显著，不良反应较少。

Comparison of the effect of propofol,fentanyl and midazolam dose intravenous anesthesia in obstetrics and gynecology

Objective To analyze the anesthetic effects of propofol ,fentanyl and midazolam dose clinical ap-plications in obstetrics and gynecology .Methods 120 cases were treated in our hospital obstetrics and gynecology outpatient surgery in accordance with the order of treatment ,who were randomly divided into control group and obser-vation group,control group were treated with propofol and fentanyl anesthesia ,observe group were treated with propo-fol,fentanyl and midazolam anesthesia small doses .During surgery,contrast-detected the patient′s respiratory groups （RR）,heart rate（HR）,pulse oxygen saturation（SaO2） and mean arterial pressure（MAR）,recorded the onset time of anesthesia,recovery time,propofol and adverse reactions and so on .Results In the control group of patients after an-esthesia RR,HR,SaO2 ,MAR before anesthesia compared with the lowest value ,and the difference were statistically significant（t=6.328,P〈0.01;t=9.917,P〈0.01;t=9.476,P〈0.01;t=4.458,P〈0.01）;observation group were anesthetized RR,HR,SaO2,MAR lowest values before anesthesia,the differences were statistically significant （t=4.467,P〈0.01;t=9.351,P〈0.01;t=2.999,P〈0.01;t=3.979,P〈0.01）;observation group were drug onset time with propofol were significantly lower than the control group （t=4.435,P〈0.01;t=6.017,P〈0.01）, there were statistically significant difference;groups incidence of adverse reactions after surgery was not significantly different.Conclusion In obstetrics and gynecology outpatient surgery anesthesia ,propofol,fentanyl and midazolam with a small dose of anesthetic is better ,analgesic sedative effect is significant ,fewer adverse reactions occurs .