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脂肪肝患者血液指标的检测意义
引用本文:郭春霞. 脂肪肝患者血液指标的检测意义[J]. 中国基层医药, 2014, 0(10): 1470-1472
作者姓名:郭春霞
作者单位:商丘市第一人民医院检验科,河南省商丘476100
摘    要:目的:探讨脂肪肝患者血液指标的检测意义。方法选取122例脂肪肝患者为观察组与131例同期入院非脂肪肝患者为对照组,两组患者均给予血常规、血脂、肝功能等血液指标检查,比较两组患者各种血液指标之间的差异,统计肝功能指标与血脂指标的相关性。结果观察组血常规指标WBC、LYM、EO、RBC、HCT、HGB、MPV、大型血小板比率( P-LCR)显著高于对照组( t =10.694、3.584、5.427、18.65、22.857、23.014、4.217、4.684,均P<0.05),PLT显著低于对照组(t=5.631,P<0.05);观察组TG、TC、LDL-C、AST、ALT显著高于对照组(t=7.01、8.45、7.26、13.62、11.98,均P<0.05),而观察组HDL-C显著低于对照组(t=4.13,P<0.05);ALT与TC、TG呈正相关(OR=1.762,P<0.05),与HDL-C呈负相关(OR=0.745,P<0.05);AST与ALT、TC呈正相关(OR=3.678,P<0.05),ALT与AST、HDL-C、TG存在较好的线性分布关系。结论脂肪肝与非脂肪肝患者的血液指标存在显著差异,肝功能的指标与血脂指标之间的关系密切,降低血脂的含量有助于改善肝功能,为脂肪肝临床诊断与指导治疗提供依据。

关 键 词:脂肪肝  非脂肪肝  血常规  血脂  肝功能

Significance of blood indicators in patients with fatty liver
Affiliation:Guo Chunxai (Department of Clinical Laboratory, the First Peoples Hospital of Shangqiu , Shangqiu , Henan 476100, China)
Abstract:Objective To discuss the clinical significance of blood indicators in patients with fatty liver . Methods 122 patients with fatty liver were selected as the observation group ,and 131 patients with non-fatty liver were selected as the control group .All patients were given examinations of blood routine ,blood lipid,liver function. The differences of various blood indicators were compared ,and the relationship between liver function and blood lipid was analyzed.Results WBC,LYM,EO,RBC,HCT,HGB,MPV,P-LCR of the observation group were significantly higher than those of the control group ( t=10.694,3.584,5.427,18.65,22.857,23.014,4.217,4.684,all P〈0.05),and PLT of the observation group was significantly lower than that of the control group (t=5.631,P〈0.05). TG,TC,LDL-C,AST,ALT of observation group were significantly higher than those of the control group ( t=7.01, 8.45,7.26,13.62,11.98,all P〈0.05),and HDL-C of the observation group was significantly lower than control group (t=4.13,P 〈0.05).ALT was positively correlated with TC,TG(OR =1.762,P 〈0.05),and negatively correlated with HDL-C ( OR=0 .7 4 5 , P〈0 .0 5 ) .AST was positively correlated with ALT , TC ( OR=3 .6 7 8 , P〈0 .0 5 ) , ALT and AST,TG,HDL-C had good linear relationship .Conclusion The blood indexes of patients with fatty liver and non-fatty liver exist significant differences , and the relationship between the indexes of liver function and blood lipids index is close ,and reducing blood fat levels can help to improve liver function .These results provide basis for the clinical diagnosis and guide therapy of fatty liver .
Keywords:Fatty liver  Non-fatty liver  Blood routine examination  Blood fat  Liver function
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