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微柱凝胶法检测1610例O型血孕妇IgG抗体效价的研究
引用本文:张健,董建红,孙佰秀,牟文风.微柱凝胶法检测1610例O型血孕妇IgG抗体效价的研究[J].中国优生与遗传杂志,2008,16(2):67-67,90.
作者姓名:张健  董建红  孙佰秀  牟文风
作者单位:青岛市妇女儿童医疗保健中心,266011
摘    要:目的探讨应用微拉凝胶法技术检测O型血孕妇血清中IgG抗A(B)血型抗体的水平,以预防新生儿溶血病的发生。方法采用BioVue系统微柱凝胶技术,为1610例丈夫为非O型的O型血孕妇进行IgG抗体效价的检测。结果1610例O型血孕妇中,IgG抗A(B)总异常率为31.7%。结论微柱凝胶技术能够快速准确的检测孕妇血清当中的IgG抗体效价,是产前预报母子血型不合而引起HDN的有效方法。

关 键 词:微柱凝胶  血型  抗体效价
文章编号:1006-9534(2008)02-0067-02
收稿时间:2007-08-22
修稿时间:2007年8月22日

Study on the valences of serum anti. A(B) IgG in pregnants by microcolumn gel assay in 1610 cases
ZHANG Jian,et al..Study on the valences of serum anti. A(B) IgG in pregnants by microcolumn gel assay in 1610 cases[J].Chinese Journal of Birth Health & Heredity,2008,16(2):67-67,90.
Authors:ZHANG Jian  
Institution:ZHANG Jian, et al.
Abstract:Objective: To measure the valences of serum anti -A (B) IgG in pregnants by microcolumn gel assay so as to prevent the occurrence of neonatal hemolysis. Methods: 1610 pregnants with the O blood whose husbands with the other blood group expect O were choosed and the valences of serum anti - A (B) IgG were measured by microcolumn gel assay. Results: The abnormal rate of serum anti - A (B) IgG in 1610 pregnants was 31.7%. Conclusion: The microcolumn gel assay can measure the valences of serum IgG in pregnants rapidly and accurately. It was an effective method to predict HDN caused by maternal -fetal blood group incompatibility.
Keywords:Microcolumn gel  Blood group  Valences of anti- A (B) IgG
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