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骨科围手术期抗菌药物预防感染的药物经济学分析
引用本文:张玉娥,梁锦仪. 骨科围手术期抗菌药物预防感染的药物经济学分析[J]. 中国执业药师, 2009, 6(10): 33-36
作者姓名:张玉娥  梁锦仪
作者单位:1. 江门市五邑中医院/暨南大学医学院第六附属医院临床药学室,广东,江门,529000
2. 广东药学院2005级临床药学系,广东,广州,510006
基金项目:江门市第三批科技计划项目
摘    要:目的:探讨应用4种常用抗菌药物预防围手术期感染的经济效果,以寻求一种费用较低、效果显著的治疗方案。方法:回顾性调查2008年10~11月份骨科手术预防感染400份病历,进行了合理性评价,并对其使用频率高、常用的头孢硫脒、头孢替唑钠、头孢呋辛钠、头孢他啶4种抗菌药物共268份病历,运用药物经济学的成本一效果分析方法进行评价。结果:4种用药方案,头孢呋辛钠是最佳用药选择。结论:头孢呋辛钠预防围手术期感染具有成本效果优势,可作为选择治疗方案时参考。

关 键 词:药物经济学  成本-效果分析  预防围手术期感染  抗菌药物

Pharmacoeconomic Analysis of Commonly Used Antibiotics to Prevent Perioperative Infection
Zhang Yue,Liang Jinyi. Pharmacoeconomic Analysis of Commonly Used Antibiotics to Prevent Perioperative Infection[J]. China Licensed Pharmasist, 2009, 6(10): 33-36
Authors:Zhang Yue  Liang Jinyi
Affiliation:1 Department of Clinical Pharmacy, Jiangrnen Wuyi Hospital of TCM / Sixth Affiliated Hospital Jinan University Medical College, Jiangmen, 529000, China;2 Guangzhou Pharmaceutical University, Guangzhou, 510006, China)
Abstract:Objective: To investigate the economic effectiveness of four antibiotics to prevent post-operation infections and find a low-cost, effective treatment options. Methods: In reviewing and investigating 400 cases for preventing infection in Orthopedics opetation from October to November,2008, we made a rational evaluation and analyzed 268 cases applied with four kinds of antimicrobial drugs of cefathiamidine, ceftezole sodium, cefuroxime sodium and ceftazidime which are frequently and commonly used by cost-effectiveness analysis in pharmacoeconomics. Results: Among those four kinds of schemes, cefuroxime sodium is the optimal option. Conclusion: Cefuroxime sodium in perioperative prevention of infection has a cost-effectiveness advantage and can be used as reference.
Keywords:Pharmacoeconomics  Cost - effectiveness analysis  Perioperative Prevention of Infection  Antimicrobial Agents
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