感染性心内膜炎104例的临床分析

分析104例感染性心内膜炎（IE）的临床资料，其中先心病75例（72.1%)，风心病21例（20.0%)，心脏无基础病变8例（7.7%)。结果提示：（1）先心病的早期诊断、早期手术根治是减少IE发生的主要预防措施：（2）发热、贫血，栓塞，肝大和脾大等的发生率显著降低；（3）赘生物侵犯主动脉瓣的概率（44.2%)高于二尖瓣（24.7%)，且主动脉瓣IE多起病急，进展快，短期进展为顽固性心力衰竭，唯有尽早行瓣膜替换术；（4）抗生素的广泛应用使血培养性阳率下降；（5）适当的内科治疗与积极的外科治疗相结合是IE治疗的重要手段。

CLINICAL ANALYSIS OF 104 PATIENTS WITH INFECTIVE ENDOCARDITIS PATIENTS

patients with infective endocarditis were analyzed. Anong them, 75 were patients with congenital heart disease (72 1%), 21 were patients with rheumatic heart disease and 8 were patients without heart disease(7 7%). It is suggested that early diagnoses and treatment of CHD are the main pretective methods for reducing the incidence of IE; the incidence of fever, anaemia, embolism, hepatomegaly and splenomegaly, etc. declines notably; the possibility of excrescence invading aortic valve (44 2%) is higher than that of mitral valve (24 7%), and IE of aortic valve results in heart failure in a short while and the valve replacement should be done as early as possible; positive rate of blood culture declines because of extensive use of antibiotics; appropriate medical treatment combined with active surgical treatment plays an important role in the treatment of IE.