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Potassium-rich diet and risk of stroke: Updated meta-analysis
Institution:1. University of Tennessee Health Science Center, Memphis, TN;2. Johns Hopkins University School of Medicine, Baltimore, MD;3. Suburban Dialysis, Williamsville, NY;4. Davita, Inc, Denver, CO;5. Baylor University Medical Center, Baylor Heart and Vascular Institute, Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, TX;6. The Heart Hospital, Plano, TX;7. University of Texas Southwestern Medical Center, Dallas, TX;8. University of Michigan School of Medicine, Ann Arbor, MI;9. Virginia Commonwealth University, Richmond, VA;10. Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA;1. Department of Medicine, Baylor College of Medicine, Methodist Hospital, and Renal Section, Veterans Affairs Medical Center, Houston, TX;2. Department of Medicine, Tufts University School of Medicine and Division of Nephrology, St. Elizabeth''s Medical Center, Boston, MA;2. Department of Medicine, Houston Methodist Hospital, Houston, TX;3. Renal Section, Veterans Affairs Medical Center, Houston, TX;4. Department of Medicine, Tufts University School of Medicine, Boston, MA
Abstract:Recently a few prospective population studies provided additional and heterogeneous information concerning the reported statistical associations between potassium (K) intake and stroke risk. Therefore, we updated our previous meta-analysis of K intake and risk of cerebrovascular events.Three studies were added to the previous analysis, and the results of the comparison between the event rate in the two extreme categories of K intake were used. Pooled analysis of 14 cohorts (overall 333,250 participants and 10,659 events) showed an inverse and significant association between K intake and risk of stroke (Relative Risk: 0.80; 95% CI: 0.72–0.90).Our results indicated a favorable effect of higher K intake on risk of stroke. These results confirm the appropriateness of worldwide recommendations for a population increased consumption of potassium-rich foods to prevent cardiovascular disease.
Keywords:Potassium  Stroke  Meta-analysis  Diet
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