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Epidemiology of Vancomycin-Resistant Enterococci in Canadian Hospitals (CANWARD Study, 2007 to 2013)
Authors:P. J. Simner  H. Adam  M. Baxter  M. McCracken  G. Golding  J. A. Karlowsky  K. Nichol  P. Lagacé-Wiens  M. W. Gilmour  Canadian Antimicrobial Resistance Alliance (CARA)   D. J. Hoban  G. G. Zhanel
Affiliation:aDiagnostic Services Manitoba, Winnipeg, Manitoba, Canada;bUniversity of Manitoba, Department of Medical Microbiology and Infectious Diseases, Winnipeg, Manitoba, Canada;cNational Microbiology Laboratory, Public Health Agency of Canada, Winnipeg, Manitoba, Canada
Abstract:Of 1,927 Enterococcus species isolates collected across Canada from 2007 to 2013, 80 (4.2%) were identified as vancomycin-resistant enterococci (VRE). VRE infections during this time tripled in Canadian hospitals, from 1.8% to 6.0% (P = 0.03). All VRE were Enterococcus faecium, with 90% possessing vanA. The prevalence of vanB decreased from 37.5% in 2007 to 0% in 2013 (P < 0.05). The VRE were multidrug resistant, but 70.6%, 86.3%, and 100% were susceptible to doxycycline, linezolid, and daptomycin, respectively.
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