心外科重症监护病房鲍氏不动杆菌耐药性分析

目的 分析心外科重症监护病房鲍氏不动杆菌耐药情况,了解其现状,为控制感染和临床治疗提供可靠依据.方法 对2008年心外科重症监护病房的感染标本采用常规方法分离细菌,对所分离的细菌使用VITEK-Jr全自动细菌鉴定仪鉴定菌种,并用GNS-133药敏卡测定鲍氏不动杆菌对13种抗菌药物的体外药敏结果,并使用扩散法进行头孢哌酮/舒巴坦的药敏试验;利用WHO所提供WHONET-5软件进行统计.结果 在14种抗菌药物中,亚胺培南耐药率为74.4%;氨苄西林耐药率100.0%;氨基糖苷类抗菌药物阿米卡星、庆大霉素和妥布霉素耐药率分别为93.0%、93.0%和88.4%;其他抗菌药物,包括第三代头孢菌素、氟喹诺酮类、复方新诺明、哌拉西林等抗菌药物的耐药率均>70.0%,仅有头孢哌酮/舒巴坦耐药率18.6%,敏感率为41.9%.结论 鲍氏不动杆菌对于抗菌药物多药耐药现象严重,仅头孢哌酮/舒巴坦敏感率>40.0%,应继续加强对该菌耐药性的监测.

Antibiotic Resistance of Acinetobacter baumannii in ICU

OBJECTIVE To analyse the infection of Acinetobacter baumannii (ABA) in ICU of Cardiac Surgery, and make analysis for its resistance to 14 antibiotics. METHODS The collection of clinic stains of ABA isolated from ICU in 2008. The pathogens were identified by VITEK-Jr. RESULTS The drug resistance rates of Imipenem and cefoperazone/sulbaetam were 74.4% and 18. 6%. The resistance rates to other drugs were more than 70%.CONCLUSIONS ABA strains isolated show the trend of muhi-durg resistance. We should pay more attention to the monitor of the resistance to antibiotics.