| Can a Tissue-Engineered Skin Graft Improve Healing of Lower Extremity Foot Wounds after Revascularization? |
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| 引用本文： | Chang DW,Sanchez LA,Veith FJ,Wain RA,Okhi T,Suggs WD. Can a Tissue-Engineered Skin Graft Improve Healing of Lower Extremity Foot Wounds after Revascularization?[J]. Annals of vascular surgery, 2000, 14(1): 44-49. DOI: 10.1007/s100169910008 |
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| 作者姓名： | Chang DW Sanchez LA Veith FJ Wain RA Okhi T Suggs WD |
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| 摘 要： |
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Can a Tissue-Engineered Skin Graft Improve Healing of Lower Extremity Foot Wounds after Revascularization? |
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| David W. Chang,Luis A. Sanchez,Frank J. Veith,Reese A. Wain,Takao Okhi,William D. Suggs. Can a Tissue-Engineered Skin Graft Improve Healing of Lower Extremity Foot Wounds after Revascularization?[J]. Annals of vascular surgery, 2000, 14(1): 44-49. DOI: 10.1007/s100169910008 |
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| Authors: | David W. Chang Luis A. Sanchez Frank J. Veith Reese A. Wain Takao Okhi William D. Suggs |
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| Affiliation: | (1) Division of Vascular Surgery, Department of Surgery, Montefiore Medical Center/Albert Einstein College of Medicine, New York, NY, US |
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| Abstract: | p < 0.01) and the median time to complete wound closure (7 vs. 15 weeks, p= 0.0021, rank-sum test). There was no difference in the wound closure rate of meshed and unmeshed graft at 4, 8, 12, or 24 weeks (p > 0.05). Three indolent localized wound infections in the tissue-engineered skin graft group were the only complication. Tissue-engineered skin grafting can be used safely in previously ischemic wounds after lower extremity revascularization. Treatment with this graft promotes healing more rapidly and in more patients than standard moist dressings. It obviates the risk, inconvenience, and expense of donor skin harvesting, anesthesia, and hospitalization associated with autologous skin grafting. This graft may represent an advance in the treatment of previously ischemic lower extremity foot wounds. |
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