Reproduction study in rats of ginseng extract G115 |
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| Authors: | F.G. Hess R.A. Parent G.E. Cox K.R. Stevens P.J. Becci |
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| Affiliation: | Food and Drug Research Laboratories, Inc., P.O. Box 107, Route 17c, Waverly, NY 14892, USA |
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| Abstract: | The effect of ginseng extract G115 on reproductive performance was studied in two generations of Sprague-Dawley rats. Animals of both sexes were fed either control diet or diet supplemented with ginseng extract G115 at dose levels of 1.5, 5 or 15 mg/kg body weight/day. Parameters of reproduction and lactation in the treated groups were comparable to those of the controls for two generations of dams and pups. For F1 males and females, no treatment-related effects were seen in weekly body weights and food consumption, haematological and clinical chemical data, and ophthalmic, gross and histopathological examinations. The gross autopsies of F0 and F2 animals also revealed no significant treatment-related findings. |
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| Keywords: | To whom requests for reprints should be addressed. |
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