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Performance status and in-hospital mortality of elderly patients with community acquired pneumonia
Authors:Filippo Pieralli  Vieri Vannucchi  Giulia De Marzi  Antonio Mancini  Francesca Bacci  Ombretta Para  Carlo Nozzoli  Marco Falcone
Affiliation:1.Subintensiva di Medicina, Internal and Emergency Medicine Department,Azienda Ospedaliero-Universitaria Careggi,Florence,Italy;2.Internal Medicine,Santa Maria Nuova Hospital, USL Toscana Centro,Florence,Italy;3.Department of Public Health and Infectious Diseases,“Sapienza” University of Rome,Rome,Italy
Abstract:To evaluate the role of performance status evaluated by the Eastern Cooperative Oncology Group (ECOG) score in predicting 30-day mortality in subjects hospitalized for community acquired pneumonia (CAP), this was a prospective study of patients consecutively hospitalized for CAP at a large University Hospital in Italy. Performance status was evaluated using the ECOG score that in a 0–5 point scale indicates progressive functional deterioration. The end-point of the study is the 30-day mortality. Two-hundred-sixteen patients were enrolled, 75.9% were aged?>?70 years, 31.5% had severe pneumonia at CURB-65 score (3–4), and 27.5% of patients had severe disability (ECOG 3–4). Thirty-day mortality is 15.3%. Progression in ECOG score independently increases the probability of 30-day mortality at multivariable logistic regression analysis (HR 2.19, 95% CI 1.60–3.01, p?p?
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