| 兔急性局限性颅高压模型经颅多谱勒频谱参数与脑灌注压相关性的研究 |
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| 引用本文： | 陈兵,刘运生,莫大鹏,李臻琰,刘尚明. 兔急性局限性颅高压模型经颅多谱勒频谱参数与脑灌注压相关性的研究[J]. 中国现代医学杂志, 2002, 12(11): 32-34 |
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| 作者姓名： | 陈兵 刘运生 莫大鹏 李臻琰 刘尚明 |
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| 作者单位： | 中南大学湘雅医院神经外科,长沙,410008 |
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| 基金项目： | 卫生部资助项目 (编号 :98-1-113 ) |
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| 摘 要： | 目的 :应用新西兰兔急性局限性颅高压模型 ,研究经颅多谱勒频谱参数与脑灌注压的关系。方法 :2 0只新西兰兔随机分为二组 ,实验组 12只 ,间断硬膜外水囊注水 ,TCD持续监测 ,直至动物死亡为止 ;对照组 8只 ,水囊不注水 ,TCD持续监测同样时间。结果 :随着ICP的升高 ,CPP降低 ;经颅多谱勒参数与CPP有一定关系 ,相关性强弱依次为 :RI>PI >cf=ce >Vd >Vm >Vs。结论 :经颅多谱勒参数可以定量地反映颅高压时脑灌注压的改变。
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| 关 键 词： | 经颅多谱勒 颅高压 脑灌注压 参数 |
| 修稿时间： | 2002-01-05 |
CORRELATION BETWEEN TRANSCRANIAL DOPPLER AN DCEREBRAL PERFUSION PRESSURE IN ACUTE LOCALIZED ICH RABBIT MODEL |
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| Chen Bing,Liu Yunsheng,Mo Dapeng,et al.. CORRELATION BETWEEN TRANSCRANIAL DOPPLER AN DCEREBRAL PERFUSION PRESSURE IN ACUTE LOCALIZED ICH RABBIT MODEL[J]. China Journal of Modern Medicine, 2002, 12(11): 32-34 |
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| Authors: | Chen Bing Liu Yunsheng Mo Dapeng et al. |
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| Affiliation: | Chen Bing,Liu Yunsheng,Mo Dapeng,et al. Department of Neurosurgery,XiangYa Hospital of Central South University,Changsha 410008 |
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| Abstract: | Objective:To evaluate the correlation between the parameters of TCD and cerebral perfusion pressure of acute localized intracranial hypertension model of New Zealand white rabbits. Methods:We divided 20 New Zealand white rabbits radomly into two groups, the experimental group (n=12) and control group (n=8). TCD in different time and different intracranial pressure was monitored in experimental group constantly until the animal died. TCD in control group was monitored at the same time.Results:The increase of ICP in experimental group was accordance with the dcrease of CPP and the parameters of TCD correlated with CPP tightly. The order of these parameters was RI>PI>cf=ce>Vd>Vm>Vs according to their contribution. Conclusions:CPP of this ICP model can be calculated by analyzing these parameters of TCD. |
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| Keywords: | TCD ICH CPP Parameters |
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