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New insights on the modulatory roles of metformin or alpha-lipoic acid versus their combination in dextran sulfate sodium-induced chronic colitis in rats
Authors:Fatma S. Samman  Samah M. Elaidy  Soha S. Essawy  Mohammad S. Hassan
Affiliation:Department of Clinical Pharmacology, Faculty of Medicine, Suez Canal University, Egypt
Abstract:
Keywords:CAT  Catalase  DAI  Disease activity index  DSS  Dextran sulfate sodium  ELISA  Enzyme linked immunoassay  IBD  Inflammatory bowel disease  IL  Interleukin  α-LA  Alpha-lipoic acid  MDA  Malondialdehyde  NF-κB  Nuclear factor-kappa-B  PBS-BSA  Phosphate-buffered saline-bovine serum albumin  SOD  Superoxide dismutase  TNF-α  Tumor necrosis factor-alpha  UC  Ulcerative colitis  Alpha-lipoic acid  Dextran sulfate sodium-induced chronic colitis  Metformin  Nuclear factor-kappa-B  Oxidative stress
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