彩色多普勒阴道超声对诊断恶性畸胎瘤的价值

目的探讨彩色多普勒阴道超声及血清甲胎蛋白（AFP）测定对诊断恶性畸胎瘤的价值。方法对2000年～2005年我院收治畸胎瘤患者465例，其中未成熟畸胎瘤13例，成熟畸胎瘤恶变3例，进行回顾性分析，着重探讨彩色多普勒阴道超声下肿物声像图特征及血流情况。部分患者进行了血清AFP测定。结果彩色多普勒阴道超声术前诊断恶性畸胎瘤及恶性卵巢肿瘤10例（10／16），符合率62．5％。未成熟畸胎瘤组9例进行了AFP测定，阳性6／9例（66．7％）；在成熟畸胎瘤恶变3例患者中，AFP均为阴性。结论彩色多普勒超声对恶性畸胎瘤诊断符合率较高，结合血清AFP含量测定，有助于对未成熟畸胎瘤，畸胎瘤恶变及卵黄囊瘤的鉴别。

Value of transvaginal color Doppler sonography in the diagnosis of malignant ovarian teratoma

Objective To evaluate the transvaginal color Doppler sonography and serum AFP in the preoperative diagnosis of malignant ovarian teratoma. Methods A total of 465 patients with teratoma, among whom 13 with immature teratoma and 3 with malignant change in benign ovary teratoma, were enrolled in the study from 2000 to 2005. The imaging features and the blood flow index were observed by transvaginal color Doppler sonography. The serum AFP was measured in part of cases. Results The accuracy rate of diagnosis with transvaginal color Doppler sonography for malignant ovarian teratoma was 62.5% (10/16). The positive rate of serum AFP of immature teratoma was 66.7%. Conclusions Transvaginal color Doppler sonography is a powerful tool in diagnosis of malignant ovarian teratoma. Serum AFP can be used as a parameter in differential diagnosis of immature teratoma, malignant change in benign ovary teratoma and yolk sac tumor.