中医辨治宫内节育器致子宫异常出血疗效观察

目的 观察加味失笑散方随症加减治疗宫内节育器致子宫异常出血的效果。方法 2011年1月至2013年3月在蕉岭县人口和计划生育服务站接收的置宫内节育器后子宫异常出血的90例患者，随机分为A组（观察组）和B组（对照组），A组用加味失笑散方随证加减治疗，B组单用加味失笑散治疗。结果 A、B两组治疗前月经量分别为(124.32±22.73)mL和(126.49±23.76) mL，治疗后月经量分别为(70.38±13.73) mL和(79.92±20.34) mL；A、B两组治疗前月经持续天数分别为(12.32±3.24) d和(11.84±3.10) d，治疗后月经持续天数分别为(6.44±1.22) d和(7.08±2.11) d；A、B两组治疗前血红蛋白分别为(113.31±11.49) g/L和(113.93±7.89) g/L，治疗后血红蛋白含量分别为(133.91±12.96) g/L和(127.62±11.34) g/L；两组月经量、月经持续天数及血红蛋白自身治疗前后比较差异均有统计学意义（P＜0.001）。治疗后A组痊愈34例(75.5%)、B组痊愈25例（55.5%），治疗后月经量、血红蛋白及痊愈率均A组为优，A、B两组比较差异均有统计学意义（P＜0.05）。结论 加味失笑散方随证加减治疗宫内节育器致子宫异常出血有较满意的效果，值得临床推广应用。

Traditional Chinese medicine treatment for intrauterine devices users with abnormal uterine bleeding.

Abstract： Objective To observe the efficacy of modified Jiawei Shixiaosan in treating abnormal uterine bleeding according to the symptoms after using intrauterine devices(IUD). Methods A total of 90 cases of abnormal uterine bleeding after using IUD were collected in the Family Planning Station of Jiaoling between Jan. 2011 and Mar. 2013.The subjects were randomly divided into group A (the observation group )and group B(the control group).Group A was treated by modified Jiawei Shixiaosan according to the symptoms,group B was treated only by Jiawei Shixiaosan.Results Before the treatment,menstrual blood volume was (124.32±22.73) mL in group A and (126.49±23.76) mL in group B,the menstrual duration was (12.32±3.24) d in group A and (11.84±3.10) d in group B,the hemoglobin content was (113.31±11.49) g/L in group A and (113.93±7.89) g/L in group B.After the treatment,the menstrual blood volume was (70.38±13.73) mL in group A and (79.92±20.34) mL in group B,the menstrual duration was (6.44±1.22) d in group A and (7.08±2.11) d in group B,the hemoglobin content was (133.91±12.96) g/L in group A and (127.62±11.34) g/L in group B.Both groups had statistical difference in menstrual blood volume,menstrual duration and hemoglobin content before and after treatment (P<0.001).After treatment, thirty-four cases (75.5%) were cured in group A and twenty-five cases (55.5%) were cured in group B .In group A,the menstrual volume was lower,the cure rates was higher and the amount of hemoglobin in the blood was more than that in group B after the treatment.There was statistical difference between group A and group B(P＜0.05). Conclusion The modified Jiawei Shixiaosan has better efficacy for IUD users with abnormal uterine bleeding which is worth being further study and apply.