200例甲状腺癌回顾性临床分析

目的 通过对经手术治疗的200例甲状腺癌患者资料分析,探讨本地区甲状腺癌发病特点及其预后相关因素.方法 对1998年1月至2009年12月本院手术治疗的200例甲状腺癌患者的临床资料进行回顾性分析.结果 本地区甲状腺癌发病率逐年增加,男女之比约1:4,男性甲状腺癌高发年龄为60～69岁,女性甲状腺癌高发年龄为50～59岁;甲状腺癌病理类型依次为乳头状癌、滤泡癌、未分化癌和髓样癌,乳头状癌所占比例显著高于其它病理类型,且各种病理类型男女比例不同.术后主要并发症为声音嘶哑、低钙抽搐和手足麻木.1、3年生存率分别为99.8%和96.7%.患者术后生存率和病理组织类型相关,预后从好到坏依次为乳头状癌、滤泡癌、髓样癌和未分化癌.结论 甲状腺癌发病率呈逐年上升趋势;乳头状癌所占比例显著高于其它病理类型甲状腺癌;手术治疗是甲状腺癌最有效治疗方式;术后生存率和病理类型相关.

A retrospective clinical analysis of thyroid carcinoma in 200 cases

Objective To study the morbidity, surgical therapy, complications and prognosis related factors of thyroid carcinoma. Methods Clinical data of 200 cases of thyroid carcinoma received surgical therapy from Jan 1998 to Dec 2009 was systematically and retrospectively analyzed. Results The ratio of incidence rate of man and woman was 1：4, which increased with years. The most frequent incidence ages of man and woman were 60 - 69 and 50 - 59 respectively. The most frequent pathologic types were papillary, follicular, anaplastic and medullar carcinoma; the papillary carcinoma was significantly more frequent than other pathologic types and they differed between man and woman. The postoperative complications were hoarseness, hypocalcemic convulsion and dead limb. 1 - year and 3 - year survival rate were 98.8% and 94. 7% respectively. Postoperative survival rate correlated with pathologic types （ P 〈 O. 05 ） ; the prognosis from well to bad was papillary, follicular, medullar and anaplastic carcinoma. Conclusion The incidence of thyroid carcinoma increases with years and papillary carcinoma is significantly more frequent than other pathologic types. Surgical therapy is the most effective curative therapy for thyroid carcinoma. Postoperative surcival rate correlates with pathologic types.