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盐酸地尔硫治疗原发性高血压病51例
引用本文:杨学义 ,韩宝福 ,陈灏珠 ,张君玮.盐酸地尔硫治疗原发性高血压病51例[J].中国新药与临床杂志,1991(4).
作者姓名:杨学义  韩宝福  陈灏珠  张君玮
作者单位:上海医药工业研究院,上海医科大学附属中山医院,上海市心血管病研究所 上海 200433,上海 200032
摘    要:原发性高血压患者51例(男28例,女23例;年龄57±SD11yr;病程13±9yr),其中,轻度11例、中度40例。用国产盐酸地尔硫(艹卓)30-90mg,tid po,4wk为一个疗程。治疗后,对轻、中度高血压总有效率分别为100%与78%,且心率减慢、二项乘积和PEP/LVET比值明显改善,不良反应轻微。

关 键 词:地尔硫/治疗应用  高血压/药物疗法  心率

Diltiazem hydrochloride therapy for 51 patients with essential hypertension
YANG Xue-Yi,HAN Bao-Fu,CHEN Hao-Zhu.Diltiazem hydrochloride therapy for 51 patients with essential hypertension[J].Chinese Journal of New Drugs and Clinical Remedies,1991(4).
Authors:YANG Xue-Yi  HAN Bao-Fu  CHEN Hao-Zhu
Abstract:Fifty one patients-(M 28, F 23; age 57±SD 11yr) with essential hypertension were treated with diltiazem hydrochloride tablets, 50 patients received 30-60 mg, tid, and 1 patient received 90 mg, tid, po. Four weeks was a course of treatment. The overall response rate of mild hypertension was 100 %, and that of moderate hypertension was 78 %. Heart rate was lowered, rate-pressure product(RPP) and PEP/LVET were improved. Adverse effects were mild.
Keywords:diltiazem/therapeutic use  hypertension/drug therapy  heart rate
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