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低分子肝素钙治疗早发型重度子痫前期临床疗效观察
引用本文:童重新,郝淑维,邢小芬,乔书花,刘琳,丁占平. 低分子肝素钙治疗早发型重度子痫前期临床疗效观察[J]. 中国妇幼保健, 2011, 26(27): 4183-4185
作者姓名:童重新  郝淑维  邢小芬  乔书花  刘琳  丁占平
作者单位:1. 河北省儿童医院妇产科 050031
2. 河北医科大学第四附属医院妇产科
基金项目:河北省科学技术研究与发展指导计划项目
摘    要:目的:观察低分子肝素钙治疗早发型重度子痫前期对母体的影响。方法:选取孕龄26~34周重度子痫前期患者60例,随机分为观察组和对照组,观察组在常规治疗基础上加用低分子肝素钙,对比两组血压、血脂、24 h尿蛋白定量、凝血纤溶功能、并发症的差异。结果:观察组平均动脉压、24 h尿蛋白、血脂TG、TC、LDL、apo-B均下降,HDL、apo-A增加,两组间差异有统计学意义(P<0.05);凝血功能无改变,纤溶活性降低,产后出血无增加,并发症降低。结论:抗凝治疗早发型重度子痫前期是有效安全的,低分子肝素钙可作为基本治疗药物之一。

关 键 词:早发型重度子痫前期  低分子肝素钙  疗效观察

Observation on the clinical curative effect of low molecular weight heparin calcium in treatment of early onset severe preeclampsia
TONG Chong-Xin,HAO Shu-Wei,XING Xiao-Fen et al. Observation on the clinical curative effect of low molecular weight heparin calcium in treatment of early onset severe preeclampsia[J]. Maternal and Child Health Care of China, 2011, 26(27): 4183-4185
Authors:TONG Chong-Xin  HAO Shu-Wei  XING Xiao-Fen et al
Affiliation:TONG Chong-Xin,HAO Shu-Wei,XING Xiao-Fen et al.Department of Gynecology and Obstetrics,Hebei Provincial Children's Hospital,Shijiazhuang 050031,Hebei,China
Abstract:Objective:To observe the effect of low molecular weight heparin calcium on the pregnant women in treatment of early onset severe preeclampsia. Methods:60 patients of 26~34 gestational weeks with severe preeclampsia were selected and divided into observation group and control group randomly.The patients in observation group were treated with additional low molecular weight heparin calcium on the basis of conventional treatment.The differences of indexes including blood pressure,blood lipids,24-hour urinary p...
Keywords:Early onset severe preeclampsia  Low molecular weight heparin calcium  Observation on the curative effect  
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