部分脾栓塞治疗门脉高压性脾功能亢进的临床研究

目的:研究部分脾栓塞治疗门静脉高压性脾功能亢进的临床意义。方法:采用Seldinger技术经股动脉插入导管至脾动脉,对15例门静脉高压、脾功能亢进患者应用40％碘化油、明胶海绵颗粒及明胶海绵条行脾脏50％～70％栓塞治疗。结果:术后3个月,脾脏明显缩小,白细胞和血小板明显回升,凝血酶原时间缩短,B超下显示门静脉、脾静脉及脾动脉缩小,随访2年患者无食道静脉曲张破裂出血及腹水出现。结论:该方法近期疗效肯定,安全、微创,适合临床普及推广。

Partial Splenic Embolotherapy Treatment on Portal Hypertension and Hypersplenia Caused by Cirrhosis

Objective: To study the clinical significance of partial splenic embolization (PSE) in treating patients with portal hypertension and hypersplenia caused by cirrhosis. Method:The partial splenic artery of 15 cases of hypersplenism with portal hypertension were embolized 50%-70% with 40% iodized oil, particulate gelatin sponge and stripe gelatin sponge by using Seldinger technique inserted tube through femoral artery. Result: The results were that spleens were shrunk and the condition of white blood cell, platelets and prothrombin. It was showed with ultrasonic B that the diameter of portal vein, splenic vein and splenic artery narrowed back. Vein of esophagus with bleeding and ascites have not been found after following 2 years. Conclusion: This technique has the features of steady therapeutic effect in short-term, safety and microtrauma.