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The potential of FDG-PET/CT for detecting prostate cancer in patients with an elevated serum PSA level

Authors:	Ryogo Minamimoto Hiroji Uemura Futoshi Sano Hideyuki Terao Yoji Nagashima Shoji Yamanaka Kazuya Shizukuishi Ukihide Tateishi Yoshinobu Kubota Tomio Inoue

Institution:	(1) Division of Nuclear Medicine, Department of Radiology, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjyuku-ku, Tokyo 162-8655, Japan;(2) Department of Radiology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan;(3) Department of Urology, Graduate School of Medicine, Yokohama City University, Yokohama, Japan;(4) Department of Molecular Pathology, Yokohama City University Graduate School of Medicine, Yokohama, Japan;(5) Division of Anatomic and Surgical Pathology, Yokohama City University Hospital, Yokohama, Japan

Abstract:	Purpose The aim of this study is to evaluate the potential and limitation of FDG-PET/CT for detecting prostate cancer in subjects with an elevated serum prostate-specific antigen (PSA) level. Although ¹⁸F]-2-fluoro-2-deoxyglucose positron emission tomography (FDG-PET) has limited value in detecting prostate cancer, the potential of PET/CT has not been precisely evaluated, since positron emission tomography/computed tomography (PET/CT) provides accurate localization of functional findings obtained by PET.

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