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| 鲁桑叶化学成分研究 | |
| 引用本文： | 韩伟立,刘利,张晓琦,叶文才,潘一乐,姚新生. 鲁桑叶化学成分研究[J]. 中国中药杂志, 2007, 32(8): 695-698 |
| 作者姓名： | 韩伟立 刘利 张晓琦 叶文才 潘一乐 姚新生 |
| 作者单位： | 1. 中国药科大学,天然药物化学教研室,江苏,南京,210009 2. 中国农业科学院,蚕业研究所,江苏,镇江,212018 3. 暨南大学,中药及天然药物研究所,广东,广州,510632 4. 中国药科大学,天然药物化学教研室,江苏,南京,210009;暨南大学,中药及天然药物研究所,广东,广州,510632 |
| 基金项目： | 国家自然科学基金;国家自然科学基金;教育部科学技术研究项目 |
| 摘 要： | 目的：研究鲁桑Morus multicaulis叶的化学成分。方法：应用离子交换树脂、硅胶和Sephadex LH-20柱色谱进行分离纯化,根据理化性质和波谱数据鉴定化合物的结构。结果：从鲁桑叶中分离得到12个化合物,分别鉴定为1-脱氧野尻霉素(1),fagomine(2),2-O-α-D-galactopyranosyl-1-deoxynojirimycin(3),槲皮素-7-O-β-D-葡萄糖苷(4),山柰酚(5),槲皮素(6),莨菪亭(7),D-天门冬氨酸(8),L-脯氨酸(9),D-α-丙氨酸(10),肌醇c(11),胡萝卜苷(12)。结论：以上12个化合物均为首次从该植物中分离得到。 |
| 关 键 词： | 鲁桑 化学成分 多羟基生物碱 黄酮 |
| 文章编号： | 1001-5302（2007）08-0695-04 |
| 收稿时间： | 2006 |
| 修稿时间： | 2006 |
Chemical constituents from leaves of Morus multicaulis |
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| HAN Wei-li; LIU Li; ZHANG Xiao-qi; YE Wen-cai;; PAN Yi-le; YAO Xin-sheng. Chemical constituents from leaves of Morus multicaulis[J]. China Journal of Chinese Materia Medica, 2007, 32(8): 695-698 | |
| Authors: | HAN Wei-li LIU Li ZHANG Xiao-qi YE Wen-cai PAN Yi-le YAO Xin-sheng |
| Affiliation: | 1. Department of Phytochemistry, China Pharmaceutical University, Nanjing 210009, China; 2. Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenfiang 212018, China; 3. Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China |
| Abstract: | OBJECTIVE: To study the chemical constituents from the leaves of Morus multicaulis. METHOD: The compounds were isolated by ion exchange resin, silica gel and Sephadex LH -20 column chromatographies. Their structures were elucidated on the basis of physico-chemical properties and spectral data. RESULT: Twelve compounds were isolated from the leaves of this plant. Their structures were identified as 1-deoxynojirimycin (1), fagomine (2), 2-O-alpha-D-galactopyranosyl-1-deoxynojirimycin (3), quercetin-7-O-beta-D-glucoside (4), kaempferol (5), quercetin (6), scopoletin (7), D-aspartic acid (8), L-proline (9), D-alpha-alanine (10), myo-inositol (11) and dausterol (12). CONCLUSION: All compounds were isolated from this plant for the first time. |
| Keywords: | Morus multicaulis chemical constituents polyhydroxylated alkaloids flavonoids |
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