湖北山麦冬化学成分的研究

从湖北山麦冬(Liriope spicata Lout(Thunb).var.prolifera Y.T.Ma)块根的醇提物中分得四种甾体甙类化合物,根据化学性质和波谱(IR,¹HNMR,¹³CNMR,EI-MS,FAB-MR)分析,确定甙Ⅰ为以β-谷甾醇为主、豆甾醇为次的混合甾醇的β-D-吡喃葡萄糖甙;甙Ⅱ为25(S)-鲁斯可皂甙元1-O-β-D-吡喃夫糖3-O-α-L-吡喃鼠李糖甙;甙Ⅲ为25(S)-鲁斯可皂甙元1-O-α-L-吡喃鼠李糖基(1→2)-β-D-吡喃木糖甙;甙Ⅳ为25(S)-鲁斯可皂甙元1-O-α-L-吡喃鼠李糖基(1→2)](β-D-吡喃木糖基(1→3)]-β-D-吡喃夫糖甙,其中甙Ⅲ和甙Ⅳ为新的甾体皂甙。

STUDIES ON THE CHEMI CAL CONSTITUENTS OF LIRIOPE SPICATA LOUR(THUNB). VAR. PROLIFERA Y.T. MA.

From the methanol extract of the roots of Liriope spicata Lour (Thunb) var. prolifera Y.T. Ma (Liliaceae) cultivated in Hubei province (China) four steroidal glycorides, tentatively named glycoside I, II, III and IV, were isolated. On the basis of chemical evidences, IR, EI-MS, FAB-MS, 1HNMR and 13CNMR analysis, structures of these glycosides were elucidated and identified as beta-sitosterol(major) and stigmasterol(minor)-beta-D-glucopyranoside (glycoside I), 25(S)-ruscogenin 1-O-beta-D-fucopyranosido-3-O-alpha-L-rhamnopyranoside (glycoside II), 25(S)-ruscogenin 1-O-alpha-L-rhamnopyranosyl(1----2)-beta-D-xylopyranoside (glycoside III) and 25(S)-ruscogenin 1-O-alpha-L-rhamnopyranosyl(1----2)] beta-D-xylopyra-nosyl(1----3)]-beta-D-fucopyranoside (glycoside IV), in which both glycoside III and glycoside IV are new steroidal saponins.