| 女儿茶多糖NLC-A的分离纯化及化学结构 |
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| 引用本文： | 焦佩玉,方积年. 女儿茶多糖NLC-A的分离纯化及化学结构[J]. 药学学报, 1989, 24(5): 353-356 |
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| 作者姓名： | 焦佩玉 方积年 |
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| 作者单位： | 湖南医药工业研究所，中国科学院上海药物研究所 长沙 410014，上海 200031 |
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| 摘 要： | 女儿茶为民间常用中草药。经水提取,去蛋白及小分子杂质得到女儿茶多糖(NLC-A)粗制品。再经Cellex D,Sepharose 6B和Sephadex G-100相继柱层析,得到均一组分NLC-A,分子量为1.2×104,NLC-A经全水解,甲基化反应,过碘酸盐氧化,Smith降解,KI-I2反应和IR证明其结构为以α(1→4)-D-葡萄糖为主链,并在o-6位有分枝的葡聚糖。
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| 关 键 词： | 女儿茶 女儿茶多糖 葡聚糖 |
| 收稿时间： | 1988-03-02 |
STUDIES ON ISOLATION, PURIFICATION AND STRUCTURE OF NLC-A OF RHAMNUS HETEROPHYLLUS |
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| PY Jiao and JN Fang. STUDIES ON ISOLATION, PURIFICATION AND STRUCTURE OF NLC-A OF RHAMNUS HETEROPHYLLUS[J]. Acta pharmaceutica Sinica, 1989, 24(5): 353-356 |
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| Authors: | PY Jiao and JN Fang |
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| Abstract: | A water-soluble glucan, NLC-A, from the roots of Rhamnus heterophyllus Olive was obtained as a homogeneous component as determined by HPLC. NLC-A was shown to compose of D-glucose, and its MW was estimated to be 1.2 x 10(4). Methylation analysis, peroxidation analysis, Smith degradation and reaction with I2-KI showed that NLC-A is a (1----4) linked alpha-D-glucan to which are attached glucosyl side chains at 0-6 of the glucosyl residues of the main chain. |
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| Keywords: | Rhamnus heterophyllus Olive Polysaccharide Glucan. |
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