国产沉香化学成分研究 Ⅳ.2-(2-苯乙基)色酮类化合物的分离与鉴定

自国产沉香(Lignum Aquilariae sinensis)属瑞香科(Thymeleaceae)植物]的乙醇提取物的乙醚溶解部分中分离得到六个2-(2-苯乙基)色酮类化合物。经光谱(UV,IR,¹HNMR ¹³CNMR和MS)分析及化学合成,确定其中一个为新化合物,即6-羟基-2-2-(4-甲氧基苯)乙基]色酮(Ⅴ)。其余五个为已知化合物,即2-(2-苯乙基)色酮,6-氧基-2-(2-苯乙基)色酮,6,7-二甲氧基-2-(2-苯乙基)色酮,6-甲氧基-2-2-(3′-甲氧基苯)乙基]色酮和6-羟基-2-(2-苯乙基)色酮,这些化合物均是首次从该植物中分离得到。

Studies on the chemical constituents of Aquilaria sinensis(Lour.) Gilg. IV. Isolation and characterization of 2-(2-phenylethyl)chromone derivatives

Six chromone derivatives were isolated from the ether soluble fraction of the alcoholic extract of Aquilaria sinensis(Lour.) Gilg. (Thymeleaceae) by silica gel chromatography. On the basis of spectrometric data (UV, IR, 1HNMR and 13CNMR as well as MS) and chemical synthesis one of them was found to be a new chromone, 6-hydroxy-2-2-(4'-methoxylphenyl)ethyl]chromone(VI) and the other five known chromones are 2-(2-phenylethyl)chromone(I), 6-methoxy-2-(2-phenylethyl)chromone (II), 6.7-dimethoxy-2-(2-phenylethyl)chromone(III), 6-methoxy-22-(3'-methoxyphenyl)ethyl]chromone(IV) and 6-hydroxy-2-(2-phenylethyl) chromone(V). These compounds were obtained for the first time from this plant.