| 微电极记录在定向苍白球毁损治疗帕金森病手术中的应用 |
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| 引用本文： | 高国栋,张华,张宝国,王庆丰,贺世明,李永林,候芳,陈玲,赵继培,RP.Iacono,李勇杰.微电极记录在定向苍白球毁损治疗帕金森病手术中的应用[J].第四军医大学学报,1998(2). |
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| 作者姓名： | 高国栋 张华 张宝国 王庆丰 贺世明 李永林 候芳 陈玲 赵继培 RP.Iacono 李勇杰 |
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| 作者单位： | 第四军医大学唐都医院神经外科!西安710038，第四军医大学唐都医院神经外科!西安710038，第四军医大学唐都医院神经外科!西安710038，第四军医大学唐都医院神经外科!西安710038，第四军医大学唐都医院神经外科!西安710038，第四军医大学唐都医院神经外科!西安710038，第四军医大学唐 |
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| 摘 要： | 目的:提高苍白球毁损术的定位精度.方法:通过微电极细胞电生理记录技术对70例71次苍白球毁损术进行苍白球内细胞电生理记录,分析电信号,确定手术靶点.结果:经微电极细胞电生理记录及分析.最终手术靶点较CT靶点更换率为82.8%,手术效果显著,并发症少.结论:通过微电极细胞电生理记录技术对苍白球毁损术进行术中定位监测,能够克服个体脑内靶点在解剖上和功能上的变异,提高了定位的精确度和治疗效果.
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| 关 键 词： | 帕金森病 微电极记录 苍白球毁损术 |
Application of microelectrode recording in pallido-tomy for treatment of Parkinson's disease |
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| GAG Gun-Dong,ZHANG Hua,ZHANG Bao-Guo,WANG Qing-Feng,HE Shi-Min,LI Yong-Lin,HOU Fang,CHEN Lin,ZHAO Ji-Pei,R. P. lacono,LI Yong-Jie.Application of microelectrode recording in pallido-tomy for treatment of Parkinson''''s disease[J].Journal of the Fourth Military Medical University,1998(2). |
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| Authors: | GAG Gun-Dong ZHANG Hua ZHANG Bao-Guo WANG Qing-Feng HE Shi-Min LI Yong-Lin HOU Fang CHEN Lin ZHAO Ji-Pei R P lacono LI Yong-Jie |
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| Institution: | GAG Gun-Dong,ZHANG Hua,ZHANG Bao-Guo,WANG Qing-Feng,HE Shi-Min,LI Yong-Lin,HOU Fang,CHEN Lin,ZHAO Ji-Pei,R. P. lacono,LI Yong-JieDepartment of Neurosurgery,Tangdu Hospital,Fourth Military Medical University,Xi'an 710038 Loma Linda Medical Uni |
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| Abstract: | To increase precision of localization in pallido-tomy. Meinoas: Seventy patients with advanced Parkinson's disease underwent unilateral or bilateral posteroventral palli-dotomy by using intraoperative microelectrode recording. In operation we analyzed electrical signals and then localized the final targets. Results: By means of microelectrode recording and analysis, the final targets had been greatly changed from CT targets. The change rate was about 82. 8%. The effect of post-operation was excellent, whereas the complication was rare. Conclusion: The target localization by using microelectrode recording can overcome anatomic and functional variance of pallidum and increase precision of localization. |
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| Keywords: | Parkinson's disease microelectrode recording pallidotomy |
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