冠心病心气虚证与左心室功能及心肌缺血相关性的临床研究

目的：研究冠心病心气虚证与左心室功能和心肌供血三者的相关性。方法：以多普勒超声心动图、体表心电图等方法进行宏观辨证与生观辩证研究；党参与硝苯吡啶治疗稳定性心绞痛，进行药证结合研究。结果：（１）冠心心气下与非心气证证比组比较，左室舒张和收缩功能部分检测指标有显著性差异；左室舒张功能评价对心气虚证诊断有高敏感性（８７％），左室收缩功能则有高特异性（８８％）。（２）党参可保护左室舒张和收缩功能，改善心肌

Clinical Study on Relationship among Heart-Qi Deficiency, Left Ventricular Function and Myocardial Ischemia in Patients with Coronary Heart Disease

Objective: To study the relationship among Heart Qi Deficiency (HQD), left ventricular function and myocardial ischemia in patients with coronary heart disease (CHD). Methods: Doppler echocardiogram, electrocardiogram were used to observe 103 patients of CHD clinically. Patients of stable angina pectoris treated with Radix Codonopsitis Pilosulae (50 cases) or Nifedipine (20 cases) were observed as well. Results: Occurrence of left ventricular function insufficiency, both systolic and diastolic, was higher in CHD patients of HQD type as compared with that of non HQD type. The left ventricular diastolic function showed high susceptibility (87%) and the left venticular systolic function showed high specificity (88%) for HQD evaluation. Radix Codonopsitis Pilosulae could protect the left ventricular function and improve myocardial ischemia. Conclusions: Myocardial ischemia and blood stasis cause HQD, while the Chinese herbal medicine treatment on HQD could improve the blood stasis to alleviate myocardial ischemia effectively. The mechanism of which might be to enhance the positive diastolic and systolic function of cardiac muscles, reduce the resistance pressure and keep pressure of coronary perfusion so as to improve the blood supply of heart.