结肠切除术患者围手术期发生医院感染的危险因素分析

目的研究结肠切除术围手术期医院感染的发生情况，探讨其相关危险因素，为其预防与控制提供科学依据。方法回顾性调查广州某医院2000～2003年结肠切除术患者291例，对发生医院感染的情况及相关危险因素进行研究。结果结肠切除术围手术期发生医院感染率为11．68％；感染部位以呼吸道最常见（47．06％），其次为手术切口（38．24％）；泌尿道插管、腹腔引流时间长、糖尿病、使用H2受体拮抗剂及化疗等与结肠切除术围手术期医院感染的发生有显著关系（P〈0．05）。结论积极控制糖尿病，减少使用H2受体拮抗剂，合理和有针对性地使用抗生素，是减少结肠切除术围手术期医院感染的关键。

Study on the relative risk factors of nosocomial infection in the perioperative duration about the colon resection

Objective To study the perioperative nosocomial infection conditions and their relative risk factors about the colon resection and provide evidence of prevention against nosocomial infections. Methods A total of 291 cases of perioperative nosocomial infection about the colon resection in one hospital in Guangzhou from the year 2000 to 2003 were restrospectively investigated to analyze the relative risk factors. Results The total perioperative nosocomial infection rate was 11.68%. The respiratory tract infection was the most frequent infection site （47.06 % ）, the next being the slice for surgical operation （38.24 % ）. The time of stay the urethra and the belly cavity tube, diabetes, use of the anti-H2 suffer medicine, and chemotherapy were closely related with perioperative nosocomial infections. Conclusions Controlling Diabetes, reducing the anti-H2 suffer medicine, and using the antibiodtic medicines were key to reducing perioperative nosocomial infections reasonably.