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Poxvirus-based vaccine therapy for patients with advanced pancreatic cancer
Authors:Howard L Kaufman  Seunghee Kim-Schulze  Kelledy Manson  Gail DeRaffele  Josephine Mitcham  Kang Seok Seo  Dae Won Kim and John Marshall
Institution:(1) The Tumor Immunology Laboratory, Division of Surgical Oncology, Columbia University, New York, NY, USA;(2) The Lombardi Cancer Center, Georgetown University Medical Center, Washington, DC, USA
Abstract:

Purpose  

An open-label Phase 1 study of recombinant prime-boost poxviruses targeting CEA and MUC-1 in patients with advanced pancreatic cancer was conducted to determine safety, tolerability and obtain preliminary data on immune response and survival.
Keywords:
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