肾结石CT值与患者经皮肾镜钬激光碎石术治疗效果的关系

目的  分析肾结石CT值与患者经皮肾镜钬激光碎石术治疗效果的关系。方法  选取2016年10月~2021年8月于本院接受经皮肾镜钬激光碎石术治疗的90例肾结石患者的资料进行回顾性分析。所有患者术前均行螺旋CT扫描检查，明确结石大小并计算平均CT值，依据平均CT值大小分为两组：其中A组43例，CT值< 1000 Hu，B组47例，CT值≥1000 Hu。两组患者均经皮肾镜钬激光碎石术治疗，比较两组手术时间、单次结石清除率、术后住院时间以及并发症情况。采用Pearson相关分析CT值与手术时间的相关性，采用Spearman相关性分析结石CT值与单次结石清除率，采用Logistic多因素分析影响经皮肾镜钬激光碎石术术后结石残留的独立危险因素。结果  A组手术时间短于B组，单次结石清除率高于B组，术后并发症低于B组，组间比较差异均有统计学意义（P < 0.05）；两组术后住院时间比较差异无统计学意义（P>0.05）。相关性分析显示，CT值与手术时间呈正比，与患者结石清除率呈反比（P < 0.05）；进一步Logistic回归分析显示，结石CT值、结石表面积为经皮肾镜钬激光碎石术术后结石残留的独立危险因素。结论  肾结石CT值与患者经皮肾镜钬激光碎石术清石效率及结石清除率明显相关，且结石CT值、结石表面积是影响经皮肾镜钬激光碎石术后结石残留的独立危险因素。

Relationship between CT values of renal calculus and the outcome of holmium laser lithotripsy with percutaneous nephrolithotomy in patients

  Objective  To analyze the relationship between CT values of renal calculus and the treatment effect of percutaneous nephroscopic holmium laser lithotripsy in patients.  Methods  Ninety patients with renal calculus treated by percutaneous lithotripsy with holmium laser in our hospital from October 2016 to August 2021 were selected for retrospective analysis. All patients underwent preoperative spiral CT scan to determine the size of calculi and calculate the average CT value, and were divided into two groups according to the mean CT value: Group A (n=43) with CT value < 1000 Hu, group B (n=47) with CT value ≥1000 Hu. Patients in both groups were treated with percutaneous nephroscopic holmium laser lithotripsy. Operation time, single stone removal rate, postoperative hospital stay and complications were compared between the two groups. Pearson correlation was used to analyze the correlation between CT value and operation time, Spearman correlation was used to analyze the correlation between CT value and single stone removal rate, and Logistic multifactor analysis was used to analyze the independent risk factors affecting stone residual after percutaneous holmium laser lithotripsy.  Results  The operation time in group A was shorter than that in group B, the single stone removal rate was higher than that of group B, and the postoperative complications were lower than that in group B, with statistically significant differences (P < 0.05). There was no significant difference in postoperative hospital stay between the two groups (P>0.05). Correlation analysis showed that CT value was positively proportional to operation time and inversely proportional to stone removal rate (P < 0.05). Further Logistic regression analysis showed that CT value and stone surface area were independent risk factors for residual stones after percutaneous with holmium laser lithotripsy.  Conclusion  CT value of kidney stones is significantly correlated with stone removal efficiency and stone removal rate in patients undergoing percutaneous nephroscopic holmium laser lithotripsy, and CT value and stone surface area are independent risk factors affecting stone residual after percutaneous nephroscopic holmium laser lithotripsy.