| 95例急性心肌梗死患者血清肌钙蛋白测定分析与探讨 |
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| 引用本文： | 丁小东,葛卫华,张海峰.95例急性心肌梗死患者血清肌钙蛋白测定分析与探讨[J].检验医学与临床,2009,6(22):1901-1901,1903. |
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| 作者姓名： | 丁小东 葛卫华 张海峰 |
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| 作者单位： | 江苏省泰州市普济医院检验中心,225300 |
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| 摘 要： | 目的探讨急性心肌梗死（AMI）患者血清肌钙蛋白测定分析与价值。方法95例AMI患者，同时设健康对照组50例，观察AMI患者及健康体检者血清肌钙蛋白T（cTnT）和肌酸激酶同工酶（CK—MB）变化。结果AMI组与对照组相比，cTnT和CK—MB结果差异有统计学意义（P〈0．05）。且cTnT和CK—MB在各时间点阳性率不同，cTnT血清活性升高快，在AMI发作后4h其阳性率比较差异有统计学意义（P〈0．05）。结论cTnT可有效监测病情的发展、治疗及预后，有助于判断溶栓的疗效，并且能提示患者的预后，可以在临床推广应用。
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| 关 键 词： | 急性心肌梗死 肌钙蛋白T 肌酸激酶同工酶 |
The analysis and approach of detecting the serum troponin in the patients with acute myocardial infarction |
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| DING Xiao-dong,GE Wei-hua,ZHANG Hai-feng.The analysis and approach of detecting the serum troponin in the patients with acute myocardial infarction[J].Laboratory Medicine and Clinic,2009,6(22):1901-1901,1903. |
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| Authors: | DING Xiao-dong GE Wei-hua ZHANG Hai-feng |
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| Institution: | DING Xiao- dong,GE Wei-hua , ZHANG Hai- feng. (Department of Clinical Laboratory of Puji Hospital, Taizhou Jiangsu 225300 China) |
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| Abstract: | Objective To investigate the determination and value of serum troponin in the patients with acute myocardial infarction. Methods cTnT and CK-MB were detected in 89 cases of acute myocardial infarction patients and 52 normal control persons. Results The cTnT and CK-MB of AMI group and normal control group had highly significant difference（P〈0.05）. The masculine rate of cTnT and CK-MB at each time were different. The activity of cTnT increased quickly, and masculine rate had highly significant difference after 4h of AMI attack （P〈0.05）. Conclusion cT-nT had the effects of monitoring the development of pathogenetic condition, treatment and prognosis, and it can also help to judge the effects of thrombolysis and deserves extended application in clinic. |
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| Keywords: | acute myocardial infarction cTnT CK-MB |
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