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肿瘤病人化疗前后消化道症状的对比分析
引用本文:何海燕,朱京慈,彭娜,王淑琼,宋佶芳,刘小琼. 肿瘤病人化疗前后消化道症状的对比分析[J]. 护理研究, 2011, 25(11). DOI: 10.3969/j.issn.1009-6493.2011.11.003
作者姓名:何海燕  朱京慈  彭娜  王淑琼  宋佶芳  刘小琼
作者单位:1. 中国人民解放军第三军医大学护理学院,400038
2. 中国人民解放军第三军医大学第三附属医院大坪医院肿瘤中心,400042
基金项目:为重庆医学科研计划基金资助项目;编号2010-2-311
摘    要:[目的]了解肿瘤病人化疗前后消化道症状的变化.[方法]用自行设计的化疗消化道症状量表对100例肿瘤静脉化疗病人化疗前后消化道症状进行纵向观察;分析化疗前、化疗第1个24h、化疗第2个24h消化道症状发生率、严重程度的差异以及相互关系.[结果]在3个时相点食欲减退、口腔/咽喉干燥、味觉异常的发生率和严重程度均居前3位,口腔/咽喉疼痛、烧心/胃灼热、腹泻的发生率和严重程度均较低.在化疗第1个24h和第2个24h,食欲减退、恶心、呕吐、味觉异常、呃逆、胃/腹胀、便秘7项症状的发生率和严重程度均高于化疗前;化疗第1个24h与第2个24h比较,消化道症状发生率和症状总分差异无统计学意义,但食欲减退、味觉异常、口腔/咽喉干燥、便秘4项症状明显加重.在消化道症状总分上,化疗前对化疗第1个24h和第2个24h均有显著预测力.[结论]化疗后消化道症状发生率和严重程度总体上高于化疗前,但消化道各种症状的变化轨迹并不相同;化疗前消化道症状的发生情况与化疗后消化道症状整体负荷密切相关.临床医护人员应重视化疗前消化道症状的评估和控制,为化疗后消化道症状的预测、筛选、预防和干预提供参考.

关 键 词:肿瘤病人  化疗  消化道症状  症状进展

Contrastive analysis of digestive tract symptoms of tumor patients before and after chemotherapy
He Haiyan,Zhu Jingci,Peng Na,et al. Contrastive analysis of digestive tract symptoms of tumor patients before and after chemotherapy[J]. Chinese Nursing Researsh, 2011, 25(11). DOI: 10.3969/j.issn.1009-6493.2011.11.003
Authors:He Haiyan  Zhu Jingci  Peng Na  et al
Affiliation:He Haiyan,Zhu Jingci,Peng Na,et al(Nursing College of Third Military Medical University of PLA,Chongqing 400038 China)
Abstract:objective:To know about the difference of gastrointestinal tract symptoms(GIS) of tumor patients before and after chemotherapy.Methods:A total of 100 tumor patients treated with intravenous chemotherapy were vertically investigated with self-designed chemotherapy-related GIS inventory.The prevalence,severity degree,and correlations of GIS at three time points(before chemotherapy,the first 24 h after chemotherapy,the second 24 h after chemotherapy) were compared.Results:At three time points,anorexia,dry mout...
Keywords:tumor patients  chemotherapy  gastrointestinal tract symptom  symptom progression  
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