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The effects of the 5-hydroxytryptamine (5HT3) receptor antagonist ICS 205-930 in the carcinoid syndrome
Authors:M. O. COUPE  J. V. ANDERSON  J. A. MORRIS  E. M. ALSTEAD  S. R. BLOOM  H. J. F. HODGSON
Affiliation:Department of Medicine, Royal Postgraduate Medical School, Hammersmith Hospital, London, UK.
Abstract:Therapy for diarrhoea associated with the carcinoid syndrome is often unsatisfactory. In an open study ICS 205-930 (Sandoz Limited), a novel 5HT3-antagonist, controlled diarrhoea in five of six patients studied. This drug may be a useful advance in the symptomatic treatment of the carcinoid syndrome.
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