| 粮食中DON含量与手骨关节炎严重程度关系的研究 |
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| 引用本文： | 李群伟,李晓梅,侯海峰.粮食中DON含量与手骨关节炎严重程度关系的研究[J].中国地方病防治杂志,2005,20(6):333-335. |
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| 作者姓名： | 李群伟 李晓梅 侯海峰 |
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| 作者单位： | 泰山医学院流行病学研究所,泰安,271000 |
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| 基金项目： | 山东省教育厅计划课题（J04E06） |
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| 摘 要： | 目的 观察不同主食地区人群骨关节炎患病严重程度与粮食中真菌毒素含量之问的关系。方法 在不同主食地区拍40岁以上的常住人口右手X线片，根据关节间隙狭窄、关节软骨下硬化、囊样变及骨外侧变形等进行严重程度诊断。采集当地主食粮食样品，用气相色谱法检测粮食中的DON含量。结果 面粉中DON的平均含量为0．302μg/kg，大米中的平均含量为0．078μg／kg，两者差异显著（P〈0．001），且与骨关节炎的严重程度呈明显正相关关系。结论 粮食中真菌毒索可能是人类骨关节炎的重要致病因素。
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| 关 键 词： | 骨关节炎 面粉 大米 脱氧雪腐镰刀菌烯醇（DON） |
| 文章编号： | 1001-1889（2005）06-0333-03 |
| 收稿时间： | 2005-08-30 |
| 修稿时间： | 2005年8月30日 |
Study on the correlation of osteoarthritis severe degree and DON levels in the foodstuff |
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| LI Qun-wei,LI Xiao-mei,HOU Hai-feng.Study on the correlation of osteoarthritis severe degree and DON levels in the foodstuff[J].Chinese Journal of Control of Endemic Disenaces,2005,20(6):333-335. |
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| Authors: | LI Qun-wei LI Xiao-mei HOU Hai-feng |
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| Abstract: | Objective To study the correlation of osteoarthritis(OA) severe degree and DON levels in the staple food in different areas.Methods Local people aged over 40 years old were taken radiograph of right hand.According to the severe degree of joints changes(joint space narrowing,sub-chondral sclerosis,cyst and osteophyte) showed on the radiograph,OA were diagnosed.DON levels in the samples were detected by gas chromatography.Results DON levels in the wheat flour was much higher than those in the rice(P<0.001),and DON level was positive correlated with osteoarthritis severe degree.Conclusions Mycotoxin in the foodstuff may probably be an important risk factor for human osteoarthritis. |
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| Keywords: | Osteoarthritis Flour Rice DON |
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