The Impact of Gender on Prognosis After Non-cardiac Vascular Surgery |
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Authors: | N Grootenboer MGM Hunink S Hoeks JM Hendriks MRHM van Sambeek D Poldermans |
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Institution: | aProgram for the Assessment of Radiological Technology (ART Program), Department of Epidemiology and Department of Radiology, Erasmus MC, Rotterdam, The Netherlands;bDepartment of Vascular Surgery, Erasmus MC, Rotterdam, The Netherlands;cDepartment of Anesthesiology, Erasmus MC, Rotterdam, The Netherlands;dDepartment of Surgery, Catharina Hospital, Eindhovem, The Netherlands;eDepartment of Cardiology, Erasmus MC, Rotterdam, The Netherlands |
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Abstract: | ObjectivesThe objective was to evaluate the impact of gender on long-term survival of patients who underwent non-cardiac vascular surgery.Design, Material and MethodsOur prospectively collected data contained information on 560 patients undergoing carotid endarterectomy (CEA), 923 elective abdominal aortic aneurysm repairs (AAA) and 1046 lower limb reconstructions (LLR). Patient characteristics and long-term mortality of women were compared to that of men. Kaplan–Meier (KM) survival curves were constructed for men and women, on which we superimposed age- and sex-matched KM survival curves of the general population. Cox proportional hazards regression was used to identify risk factors for mortality.ResultsMen in the CEA group had statistically significant higher all-cause mortality, hazard rate ratio (HRR) 1.41 (95% CI 1.01–1.98) No differences in mortality between the genders were observed in the AAA and LLR groups.Overall, men had more co-morbidities but received more disease-specific medication compared to women. Women retained their higher life expectancy after CEA but lost it in the AAA and LLR groups.ConclusionWomen retain their higher life expectancy after CEA; however, after AAA repair and LLR, this advantage is lost. Both men and women received too little disease-specific medication, but women were worse off. |
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Keywords: | Gender Survival Carotid endarterectomy Abdominal aortic aneurysm repair Lower leg revascularisation Long-term follow-up |
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