冠状动脉支架置入对分支血管的影响

目的 比较观察不同药物洗脱支架及普通支架置入术后分支血管的自然发展情况,探讨分支血管闭塞及再通的影响因素。方法回顾性分析在解放军总医院心内科接受支架置入术并进行造影随访的183例患的病例资料及术前、术中、术后的造影光盘资料,分析支架覆盖的所有分支血管。结果支架术后分支血管的闭塞率是8．9％,其中Cypher药物支架组为10．5％,Taxus药物支架组为11．1％,普通支架为7．8％,72．0％的闭塞分支在随访时再通,其中Cypher组是90．9％,Taxus组为66．7％,普通支架组为66．7％;三组间差异无统计学意义;分支开口狭窄和起始部位有病变是分支血管闭塞的独立危险因素;支架内再狭窄、病变类型及分支情况等都不会影响闭塞分支的再通。结论不同类型的药物支架和普通支架在对分支血管的影响方面基本一致;分支开口狭窄和分支起始部位病变是分支血管闭塞的独立危险因素;闭塞的分支血管自然预后良好,大部分会自行再通。

The influence of coronary main vessel stenting on side branches

Objective To evaluate the influence of stenting main vessel on side branches and to compare the different effects on side branches between BMS and DES (Taxus and Cypher).Methods We reviewed the angiograms and the medical records of 183 patients who had received stent implantation in coronary main vessels and had follow-up angiograms. Any side branch was jailed by stent was evaluated.Results Side branch occlusion occurred in 8.9% in all branches (10.5% in Cypher DES group, 11.1% in Taxus DES group and 7.8% in BMS group). Spontaneous recanalization of side branches was observed in 72% (90.9% in Cypher DES, 66.7% in Taxus stent group and 66.7% in BMS). The ostial side branch stenosis before stenting and the involvement of the side branch origin within the lesion of the parent vessel are the major independent predictors for side branch occlusion.Conclusions The influence of different DES implantations in coronary main vessels on side branches were similar and there was no difference between DES and BMS. Side branch occlusion had relatively benign clinical course. Most occluded side branches had late spontaneous reperfusion.