Gender difference in antidepressant-related sexual dysfunction in Taiwan |
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| Authors: | Tzu I Lee Joana Issac Shih-Hsien Lin Tzung Lieh Yeh I Hui Lee Po See Chen Kao Chin Chen Yen Kuang Yang |
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| Institution: | 1. Department of Psychiatry, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan;2. Department of Medicine, University of Lisbon, Lisbon, Portugal;3. Addiction Research Center, National Cheng Kung University, Tainan, Taiwan;4. Department of Psychiatry, National Cheng Kung University Hospital, Dou-Liou Branch, Yunlin, Taiwan;5. Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan;6. Department of Psychiatry, College of Medicine, National Cheng Kung University, Tainan, Taiwan |
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| Abstract: | ObjectiveSexual dysfunction accompanied by depression may be altered by antidepressants. The effects of antidepressants on sexual dysfunction among males and females remain to be investigated.MethodsThree groups of subjects, drug-free patients with depression (N= 125), medicated patients with depression (N= 145) and healthy volunteers (N= 255), were recruited. A Chinese version of the Changes in Sexual Functioning Questionnaire was employed to assess sexual function as the primary outcome.ResultsDrug-free depressed females and medicated depressed males had more sexual dysfunction than healthy controls. The desire for sexual behaviors among healthy females and medicated depressed females was higher than that of drug-free depressed females.ConclusionDepression and antidepressants may have different impacts on the sexual function of males and females. |
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| Keywords: | Depression Antidepressant Sexual dysfunction Sex difference |
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