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Preoperative expiratory and inspiratory muscle weakness to predict postoperative outcomes in patients undergoing elective cardiac surgery
Authors:Eliane R Winkelmann PhD  Édina Steffens PT  Pollyana Windmöller MSc  Paula C Fontela MSc  Dante T da Cruz MD  Iara D E Battisti PhD
Institution:1. Departamento de Ciências da Vida, Universidade Regional do Noroeste do Estado do Rio Grande do Sul, Ijuí, Rio Grande do Sul, Brasil;2. Faculdade de Medicina, Programa de Pós-Graduação em Ciências Pneumológicas, Universidade Federal do Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brasil

Unidade de Terapia Intensiva Coronariana, Instituto do Coração, Hospital de Caridade de Ijuí, Ijuí, Rio Grande do Sul, Brasil;3. Unidade de Terapia Intensiva Coronariana, Instituto do Coração, Hospital de Caridade de Ijuí, Ijuí, Rio Grande do Sul, Brasil;4. Programa de Pós-Graduação em Ambiente e Tecnologias Sustentáveis e Programa de Pós-Graduação em Desenvolvimento e Políticas Públicas, Universidade Federal da Fronteira Sul, Campus Cerro Largo, Cerro Largo, Rio Grande do Sul, Brasil

Abstract:Background: Few studies have evaluated preoperative respiratory muscle strength as a risk factor for postoperative morbidity and mortality. The objective of this study was to evaluate the association of preoperative inspiratory muscle weakness (IMW) and preoperative expiratory muscle weakness (EMW) with duration of mechanical ventilation, length of stay in the intensive care unit (ICU), incidence of postoperative pulmonary complications (PPCs), and mortality in patients undergoing elective cardiac surgery. Materials and methods: This was a prospective observational study. Patients admitted for elective cardiac surgery were recruited. Maximal inspiratory and expiratory pressure were measured before surgery. A multivariate regression model was used to adjust for possible confounding variables and test the association of IMW and EMW with the duration of mechanical ventilation, length of stay in the ICU, PPCs, and hospital mortality. Results: Two hundred and fifty-five patients were included in this study. The presence of IMW was associated with an increase in the duration of mechanical ventilation (P = .012). The presence of EMW was associated with a reduction in the incidence of PPCs (P = .005). IMW had no significant association with length of stay in the ICU, PPCs, or hospital mortality. EMW had no significant association with the duration of mechanical ventilation, length of stay in the ICU, or hospital mortality. Conclusions: In patients undergoing elective cardiac surgery, preoperative IMW is associated with the duration of mechanical ventilation while preoperative EMW is associated with a decrease in PPCs.
Keywords:length of hospital stay  mortality  muscle strength  physical therapy  postoperative pulmonary complications  thoracic surgery
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