小儿急性呼吸道感染C-反应蛋白测定价值的探讨

目的:探讨急性呼吸道感染患儿血清C-反应蛋白(CRP)水平变化及临床价值。方法:检测178例急性呼吸道感染患儿和50例健康儿童的血清CRP水平及WBC总数及分类计数。结果:107例细菌感染组患儿与对照组比较血清CRP明显升高(P<0.01)。71例病毒感染组患儿与对照组比较差异无显著性(P>0.05),若以8mg/L为两者的临界点,细菌感染组阳性率为100％(107/107),而病毒感染组为0％(0/71)。结论:在小儿急性呼吸道感染时检测血清CRP水平可正确灵敏地鉴别感染的致病病原体,有助于临床作及时的针对性治疗,值得推广应用。

Exploration of Clinical Value of Detecting C-reactive Protein Level in Children with Acute Respiratory Infection

Objective: To explore the level of serum C-reactive protein (CRP) and clinical value in patients with acute respiratory infection (ARI) . Methods: The serum CRP level and the total and classifed count of white blood cell (WBC) were detected in 178 children with acute respiratory infection (infected group) and 50 healthy childred (control group). Results: The serum CRP level in infected group was significantly higher than that in control group ( P < 0.01) , but there was no significant variation between 71 children infected by virus (from the infected group) and the controul group ( P > 0.05) . If 8mg/L was used as critical-point for both, the positive rate was 100% in children infected by bacterium (107/107) , and 0% (0/71) in children! infected by virus. Conclusion: Detection of serum CRP level in the patients with acute respiratory infection may help to correct and sensitive establish the pathogen and to directly treat the disease.